John S. Duncan, Chair
|Tom Henry, Secretary
|Fernando Lopes da Silva
Bilthoven, The Netherlands
The DMC subcommissions are as follows: Neuroimaging (Chair: Tom
Henry). Definitions of epilepsy (Chair: Robert Fisher). Video description
of seizures (Chair: Ian Mothersill). Neurophysiology (Chair: Fernando
Lopes da Silva). Neuropsychology (Chair: Marilyn Jones Gotman).
Neuroimaging Chair: T. Henry (USA); Secretary: F. Cendes (Brazil).
Members: R. Bronen (USA), J. S. Duncan (UK), C. Chiron (France),
W. Gaillard (USA), R. Kuzniecky (USA), I. Savic (Sweden), P. Satishchandra
Neuroimaging Subcommission Objectives
- Recommendations on neuroimaging of children with epilepsy.
- Recommendations on the standardization of
imaging formats between centers.
- Review of the current situation on neuroimaging in animal
models of epilepsy.
- Review of the current situation on neuroimaging and the
biology of the epilepsies including
development, neuroprotection, plasticity and genetics.
- Planning and presentation of the Imaging Skills Workshop
at the International Epilepsy Congress in 2003.
Definition of Epilepsy
Chair: R. Fisher (Stanford, USA), W. Emde Boas (Netherlands),
Warren Blume (London, Canada), Christian Elger (Bonn, Germany),
Pierre Genton (Marseille, France), Jerome Engel, Jr. (Los Angeles,
USA), Phillip Lee (London, UK).
1. Document on definitions of epilepsy and of seizures.
Chair: M. Jones Gotman (Montreal, Canada); Secretary: Mary Lou
Smith (Ontario, Canada). Members: Gail Risse (Minnesota, USA),
Michael Westerveld (Connecticut, USA), Susan Bookheimer (California,
USA), Sally Baxendale (London, UK), Anna Rita Giovagnoli (Milan,
Italy), Tatia Lee (Hong Kong), Michael Saling (Melbourne, Australia).
- Recommendations on minimum standards for neuropsychological
assessment prior to epilepsy surgery.
Video Classification of Seizures
Chair: I. Mothersill (Zurich, Switzerland); Secretary: P. Hilfiker
(Zurich, Switzerland). Members: T. Grunwald (Bonn, Germany), A.
Ebner (Bethel, Germany), W. van Emde Boas (Amsterdam, Netherlands),
J. Alving (Denmark), W. Blume (London, Canada).
- Dissemination of “Signs of Epileptic Seizures CD” (Completed)
- Production of Nonepileptic Attacks CD.
Chair: F. Lopes da Silva (Netherlands); Secretary: G. Battaglia
(Italy). Members: Jean Gotman (Canada), Brian Litt (USA), Bernard
Renault (France), Klaus Lennertz (Germany), Dimitri Velis (Netherlands),
Sylvia Kochen (Argentina), Perrine Plouin (France).
- Recommendations for standardization of digital EEG format
for intersite transmission.
Achievements prior to
Each subcommission agreed on objectives to pursue over the next
4 years, in the form of producing guidelines and consensus statements
that relate to
their areas of expertise, and the organization of teaching skills
workshops, in order to disseminate best practice.
Commission Activities July 31, 2003 to June 30, 2004
Three one-day skills workshops were held at the 25th IEC in Lisbon
on Saturday 11 October 2003, covering Neuroimaging, Neuropsychology
and Neuro-physiology. US $20,000 of external sponsorship was obtained
and the workshops were a success. Attendance was lower than previously
because the advertising of the workshops in the conference materials
was poor and many potential attendees did not know of their existence
Neuroimaging progress towards objectives. C. Chiron and G. Gaillard
have drafted recommendations for imaging children. Subcommission
members agreed that it would be desirable to recruit other participants,
probably basic scientists who are not active in the ILAE, to assist
us in the third and fourth objectives. T. Henry is working on this
area. The second objective is problematic, owing to the principal
role that neuroradiologists hold in determination of imaging formats,
and the considerable independence of various national and center-specific
organisations in technical aspects of imaging. R. Bronen is working
on opinions as to what if anything would be desirable to review
Definition of Epilepsy
Progress towards objectives. R. Fisher and colleagues have agreed
upon definitions for the terms “epileptic seizures” and “epilepsy.” A
paper has been written and submitted to the ILAE Executive Committee.
Progress towards objectives. Topics being reviewed with the intent
to write documents are:
- Identify reliable neuropsychological localizing tasks.
- Find standard expression of performance. Examples of tests
that assess these functions could be provided. The emphasis
should be placed on the logic behind an assessment rather than
a particular battery of tests.
- Determine our role in Quality of Life issues
- Define the interface of functional neuroimaging with neuropsychological
- Define the current role of the intracarotid amytal procedure
in presurgical evaluation.
Video Classification of Seizures
Progress towards objectives. Nihon Kohden and Aventis have purchased
and distributed copies of the CD-ROM “Signs of Epileptic
Seizures” to distribute among their customers. The disseminaton
of “Signs of Epileptic Seizures” is finally completed.
The next project “Non-Epileptic Attacks” is still
waiting for sponsorship. Due to the advances in DVD technology
the next production will probably be combined with from signs to
seizures, i.e., which sign occurs in which seizure type and then
comparing the epileptic seizures to non-epileptic attacks that
could cause diagnostic difficulties.
Progress towards objectives. Regarding the recommendations for
standardization of digital EEG
format, a discussion among subcommittee members has led to enlarging
the scope of this issue to account for more general recommendations
regarding the requirements for long-term recordings in epilepsy.
A position paper on this issue is being
We have set up an integrated Diagnostic Methods workshop for the
26th IEC in Paris, to be held on Saturday, 27 August 2005. In addition,
subcommissions are working on completing their objectives.
John S. Duncan