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Looking forward to the
31st International Epilepsy Congress

5 - 9 September, 2015 – Istanbul, Turkey www.epilepsyistanbul2015.org

Register now

International Epilepsy Congress 2015 Istanbul

Advances in the treatment of status epilepticus

Historical Peninsula

This session on Wednesday, September 9, will start with a lecture by Jaideep Kapur (USA) on the translation of animal findings to the human situation. Eugen Trinka (Austria) will then discuss treatment options after failure of response to benzodiazepines and Simon Shorvon (UK) will address the management of super-refractory status epilepticus.

What's on for the pediatric epileptologists?

Beyoglu Trams

The Congress offers a uniquely rich programme for delegates who have an interest in the diagnosis and management of epilepsy in neonates, infants and children. Relevant sessions include “Acute neonatal seizures on early onset epilepsy: Challenges of early recognition and implications for management,” “Personalizing mTOR inhibition for epilepsy treatment: From bench to bedside,” “Epilepsy and autism: Co-occurrence and potential commonalities during brain development,” “Epileptic encephalopathies,” and many more.

More highlights | Congress Program | Register now

News from ILAE All news

ILAE Annual Report

ILAE Annual Report 2014

The 2014 ILAE Annual Report is now available. The Report outlines work and accomplishments for the period of July 2013 – June 2014 and includes reports from the ILAE Executive, Regional and Topic-Oriented Commissions as well as ILAE Chapters around the world.




ILAE Position on "Stop Vivisection Initiative"

European Union

The ILAE and IBE Executive Committees, the AES-ILAE Translational Research Task Force, and the Neurobiology Commission of the ILAE have prepared a response to the members of the European Parliament to oppose the March 3rd, 2015, European Citizens Initiative Stop Vivisection. This initiative requests the phasing out of animal experimentation in biomedical research in Europe. Discussion and voting on this initiative is expected over the next 1-2 months.

The position of the ILAE-IBE is that this initiative is deleterious for the future of biomedical research, and is summarized here. If you agree with our position, we urge you to join our efforts to disseminate and clarify our position to those who may inform the voting Members of the European Parliament so that this initiative is not voted. Read position summary.

Epigraph 2015 issue 1

Epigraph - ILAE Newsletter

From the Information Officer | From the Vice President | Traditional Healers | First Francophone Teaching Course | Building Infrastructure in Africa | Preventing Epilepsy After Injury | Preventing Death in Epilepsy | Awards | Obituary: Yukio Fukuyama | Obituary: Karen Gale | EpiNet | ILAE Journals | Upcoming Congresses

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News Around the World All news

First Epilepsy Brain Bank in Canada

Epilepsy Brain Bank

The Epilepsy Brain Bank at the College of Medicine at the University of Saskatchewan is one of the first epilepsy-centric brain banks in Canada, and the first focused solely on adult epilepsy research. It was established by a team led by Dr José Tellez-Zenteno, Dr. Farzad Moien-Afshari, Dr. Adam Wu and Dr. Lizbeth Hernandez-Ronquillo

CLAE Connections | U. of Saskatchewan article |
Star Phoenix | CTV (video)

Karen Gale (1948-2014)

Karen Gale

The epilepsy community lost a truly unique and powerful voice with the recent death of Karen Gale, Professor of Pharmacology at Georgetown University in Washington, D.C. and one of the founders and the director of the Georgetown Interdisciplinary Program in Neuroscience. Karen had a research agenda that was as wide as her active intellect, and her recent work on the comorbidities of epilepsy including deleterious effects of antiepileptic compounds on neural development has stimulated great discussion within the epilepsy community. Although Dr. Gale left an indelible mark as a researcher and educator, she is perhaps best known as a stalwart advocate for faculty, students and staff.
Read Karen Gale's obituary.

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Clinical Research News All news

Treatment of infants with epilepsy: Common practices around the world

High quality data to guide recommendations for infants with epilepsy are lacking. This study aimed to develop an understanding of common practice and regional variations in the treatment interventions of infants with epilepsy, and also to identify areas for further study and to highlight where common practice occurs without sound evidence. (Epilepsia DOI: 10.1111/epi.13003)

IQ improves after antiepileptic drug withdrawal following pediatric epilepsy surgery

Antiepileptic drugs (AEDs) have cognitive side effects that, particularly in children, may affect intellectual functioning. With the TimeToStop study, we showed that timing of AED withdrawal does not majorly influence long-term seizure outcomes. We now aimed to evaluate the effect of AED withdrawal on postoperative IQ, and change in IQ (delta IQ) following pediatric epilepsy surgery … (Annals of Neurology DOI: 10.1002/ana.24427)

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Basic Science of Epilepsy News All news

Astrocyte uncoupling as a cause of human temporal lobe epilepsy

Astrogliosis (marked by hypertrophy of astrocytes and upregulation of astrocyte-specific markers) has been suggested to be proconvulsive in temporal lobe epilepsy. In this study, the authors show that there is loss of gap junction coupling between astrocytes in tissue resected from people with epilepsy with hippocampal sclerosis; this could underlie improper buffering of K+ ions. … Using an animal model of epilepsy, the authors also show that astrocytic uncoupling is a fairly early process in epileptogenesis. Hence, one can hypothesize that halting astrocytic uncoupling after an initiating event could stop epileptogenesis.

Caret image Summary for non-specialists

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy model

Studying inflammation could give us insights into novel drugs for seizure disorders. In this study, the researchers examined a certain pro-inflammatory complement peptide C5a and its receptor C5ar1 in experimental epilepsy. (Neurobiology of Disease 76(2015) 87-97)

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Epileptic Disorders

Editor's Choice:
Concept of epilepsy surgery and presurgical evaluation. Comments by Associate Editor Silvia Kochen

Caret image More about Epileptic Disorders


Chapter Spotlight:

Canadian Epilepsy Foundaton

Since its founding in 1977, the Canadian League Against Epilepsy has worked to enable Canadians affected by epilepsy to live a life that is not limited by their condition. In recent months, our chapter has launched a number of new committees and funding opportunities to increase our success at achieving our goals and mission.

Caret image Read about recent Canadian League activities


VIREPA Applications Now Open

Applications for the 2015-2016 Academic Year will be accepted from May 18 – August 3.

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ILAE eNewsletter

Free monthly email newsletter with brief highights of the ILAE's activities.

To subscribe, please provide your email address:

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Definition of Epilepsy 2014 - New definition and commentaries.

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