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Management Committee Election

Management Committee elections are now underway, and will conclude 9 November. Each Chapter has received a single ballot on which they may select five candidates. The following are candidates for the roles of Secretary General, Treasurer, and Vice President.

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Edward Bertram
Edward Bertram

Roberto Caraballo
Roberto Caraballo

Fernando Cendes
Fernando Cendes

Helen Cross
Helen Cross

Alla Guekht
Alla Guekht

Angelina Kakooza
Angelina Kakooza

Andres Kanner
Andres Kanner

Byung In Lee
Byung In Lee

Shichuo Li
Shichuo Li

Man Mohan Mehndiratta
Man Mohan

Chanez Charfi Triki
Chahnez Triki

Sam Wiebe
Jo Wilmshurst

News from ILAE All news

New Epileptologist Competencies Survey

The ILAE is developing an educational curriculum for Epileptologists.We need you to help us identify the competencies that are important for training Epileptologists and that should be included in an educational curriculum. This is an anonymous survey. Complete survey here: www.surveymonkey.com/r/epileptologistcompetencies

ILAE Epigraph Newsletter

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From the Information Officer | From the President | Brain Recovery Project | Epilepsy Care in Canada | Epilepsy Education in Latin America | EpilepsyDiagnosis.org | Epilepsy Awareness Day | 20th Anniversary of Thai Epilepsy Society | ILAE Journals | Upcoming Congresses | Download complete issue as PDF

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News Around the World All news

Putting Epilepsy in the Picture

International Epilepsy Day

Art Competition to celebrate International Epilepsy Day 2017
Entry deadline: 31 December 2016

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Farewell: Uwe Heinemann

Uwe Heinemann

The epilepsy community lost one of its leading researchers and mentors with the death of Uwe Heinemann on September 8, 2016. At the time of his death, Uwe was a Senior Professor at the Charité in Berlin where he had been a Professor of Neurophysiology and Neuroscience for the last 23 years. He was a leading and passionate researcher in epilepsy with an insatiable desire to understand its causes and the causes of drug resistance. He also studied the brain circuits that support seizures, and in those studies helped us to understand how the brain itself works. More …

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Clinical Research News All news

Idiopathic focal epilepsies: the “lost tribe”

Epileptic Disorders

The term idiopathic focal epilepsies of childhood (IFE) is not formally recognised by the ILAE in its 2010 revision (Berg et al., 2010), nor are its members and boundaries precisely delineated. The IFEs are amongst the most commonly encountered epilepsy syndromes affecting children. They are fascinating disorders that hold many “treats” for both clinicians and researchers. Epileptic Disorders, Vol 18, No. 3.

Surgical treatment of pediatric focal cortical dysplasia: Clinical spectrum and surgical outcome.

Researchers analyzed the clinical presentation and outcomes of surgically treated focal cortical dysplasia (FCD) in children and concluded that FCD can cause FE and EE in pediatric age, and resective surgery should be considered as a treatment option for both types of epilepsy. Neurology vol. 87 no. 9, 945-95.

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Basic Science of Epilepsy News All news

Tight Coupling of Astrocyte pH Dynamics to Epileptiform Activity Revealed by Genetically Encoded pH Sensors

Dynamic changes in intracellular ion concentrations are central to the initiation and progression of epileptic seizures. However, it is not known how changes in intracellular H+ concentration (ie, pH) differ between different cell types during seizures. Using recently developed pH-sensitive proteins, we demonstrate that astrocytes undergo rapid alkalinization during periods of seizure-like activity, which is in stark contrast to the acidification that occurs in neighboring neurons. (doi: 10.1523/JNEUROSCI.0664-16.2016)

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Reducing premature KCC2 expression rescues seizure susceptibility and spine morphology in atypical febrile seizures

Atypical febrile seizures are considered a risk factor for epilepsy onset and cognitive impairments later in life. Patients with temporal lobe epilepsy and a history of atypical febrile seizures often carry a cortical malformation. This association has led to the hypothesis that the presence of a cortical dysplasia exacerbates febrile seizures in infancy, in turn increasing the risk for neurological sequelae. The authors' findings demonstrate that KCC2 overexpression in a compromised developing brain increases febrile seizure susceptibility and contribute to dendritic spine alterations. (Neurobiology of Disease doi:10.1016/j.nbd.2016.02.014)

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