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Looking forward to the 31st International Epilepsy Congress

Register now!

International Epilepsy Congress 2015 Istanbul

Topkapki Palace
5 - 9 September, 2015 – Istanbul, Turkey www.epilepsyistanbul2015.org
Early Registration Deadline 22 May

Learn about the latest advances in cutting edge epilepsy research.

Leading researchers in basic and clinical sciences convene at the WONOEP workshop a few days before. the Congress to discuss the latest developments and directions in translational epilepsy research. Congress delegates will hear WONOEP Highlights, a summary of how the newest experimental findings discussed at WONOEP will change the way we diagnose and treat epilepsy in the clinic. For those delegates with a special interest in translational research, there will be a dedicated translational programme on every day of the congress. The Neurobiology Symposium will be dedicated to “Optogenetics to cure epilepsy: Facts and feasibility.”

How are genetics changing the epilepsy landscape?

The impressive advances made in understanding the genetics of the epilepsies are the topic of the Presidential Symposium which will open with an overview by Sam Berkovic (Australia). Iscia Lopes Cendes (Brazil) will then answer the key questions: “Who do I test, when do I test, how do I test, and what do I tell the patient?” Sanjay Sisodiya (UK) will provide an update on how genes affect response to treatment, including application of genetics to determine the best treatment for the individual. The results of genetic tests have many implications for the person with epilepsy: no one better than Tracy Dizon-Salazar (USA) can discuss on the pros and cons of knowing the answer. Other aspects of the genetics of epilepsy will be addressed in several parallel sessions throughout the congress.

Epilepsy imaging — not only a focus, not only a network

A session on Monday, September 7 will review evidence behind the concept of epilepsy as a network disease, the consequences of network alterations in epilepsy, and the latest applications of structural and functional imaging in identifying the epileptogenic zone. Leading speakers in this session include Fabrice Bartolomei (France), Anna Elisabetta Vaudano (Italy), Andrea Bernasconi (Canada) and Akio Ikeda (Japan).

More highlights | Congress Program | Register now

News from ILAE All news

ILAE Annual Report

ILAE Annual Report 2014

The 2014 ILAE Annual Report is now available. The Report outlines work and accomplishments for the period of July 2013 – June 2014 and includes reports from the ILAE Executive, Regional and Topic-Oriented Commissions as well as ILAE Chapters around the world.




ILAE Position on "Stop Vivisection Initiative"

European Union

The ILAE and IBE Executive Committees, the AES-ILAE Translational Research Task Force, and the Neurobiology Commission of the ILAE have prepared a response to the members of the European Parliament to oppose the March 3rd, 2015, European Citizens Initiative Stop Vivisection. This initiative requests the phasing out of animal experimentation in biomedical research in Europe. Discussion and voting on this initiative is expected over the next 1-2 months.

The position of the ILAE-IBE is that this initiative is deleterious for the future of biomedical research, and is summarized here. If you agree with our position, we urge you to join our efforts to disseminate and clarify our position to those who may inform the voting Members of the European Parliament so that this initiative is not voted. Read position summary.

Epigraph 2015 issue 1

Epigraph - ILAE Newsletter

From the Information Officer | From the Vice President | Traditional Healers | First Francophone Teaching Course | Building Infrastructure in Africa | Preventing Epilepsy After Injury | Preventing Death in Epilepsy | Awards | Obituary: Yukio Fukuyama | Obituary: Karen Gale | EpiNet | ILAE Journals | Upcoming Congresses

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News Around the World All news

First Epilepsy Brain Bank in Canada

Epilepsy Brain Bank

The Epilepsy Brain Bank at the College of Medicine at the University of Saskatchewan is one of the first epilepsy-centric brain banks in Canada, and the first focused solely on adult epilepsy research. It was established by a team led by Dr José Tellez-Zenteno, Dr. Farzad Moien-Afshari, Dr. Adam Wu and Dr. Lizbeth Hernandez-Ronquillo

CLAE Connections | U. of Saskatchewan article |
Star Phoenix | CTV (video)

Karen Gale (1948-2014)

Karen Gale

The epilepsy community lost a truly unique and powerful voice with the recent death of Karen Gale, Professor of Pharmacology at Georgetown University in Washington, D.C. and one of the founders and the director of the Georgetown Interdisciplinary Program in Neuroscience. Karen had a research agenda that was as wide as her active intellect, and her recent work on the comorbidities of epilepsy including deleterious effects of antiepileptic compounds on neural development has stimulated great discussion within the epilepsy community. Although Dr. Gale left an indelible mark as a researcher and educator, she is perhaps best known as a stalwart advocate for faculty, students and staff.
Read Karen Gale's obituary.

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Clinical Research News All news

IQ improves after antiepileptic drug withdrawal following pediatric epilepsy surgery

Antiepileptic drugs (AEDs) have cognitive side effects that, particularly in children, may affect intellectual functioning. With the TimeToStop study, we showed that timing of AED withdrawal does not majorly influence long-term seizure outcomes. We now aimed to evaluate the effect of AED withdrawal on postoperative IQ, and change in IQ (delta IQ) following pediatric epilepsy surgery … (Annals of Neurology DOI: 10.1002/ana.24427)

The ketogenic diet is an effective adjuvant to radiation therapy for the treatment of malignant glioma

Caret image Summary for non-specialists

The usefulness of the ketogenic diet has been shown in refractory epilepsy, but its use in brain tumors is still being investigated. This study showed that in mice with glioma, the ketogenic diet along with radiation was effective in shrinking tumor volume. The effect of the ketogenic diet along with radiation on seizure frequency would be interesting to observe. (PLoS ONE 7(5): e36197)

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Basic Science of Epilepsy News All news

Astrocyte uncoupling as a cause of human temporal lobe epilepsy

Astrogliosis (marked by hypertrophy of astrocytes and upregulation of astrocyte-specific markers) has been suggested to be proconvulsive in temporal lobe epilepsy. In this study, the authors show that there is loss of gap junction coupling between astrocytes in tissue resected from people with epilepsy with hippocampal sclerosis; this could underlie improper buffering of K+ ions. … Using an animal model of epilepsy, the authors also show that astrocytic uncoupling is a fairly early process in epileptogenesis. Hence, one can hypothesize that halting astrocytic uncoupling after an initiating event could stop epileptogenesis.

Caret image Summary for non-specialists

A novel anticonvulsant mechanism via inhibition of complement receptor C5ar1 in murine epilepsy model

Studying inflammation could give us insights into novel drugs for seizure disorders. In this study, the researchers examined a certain pro-inflammatory complement peptide C5a and its receptor C5ar1 in experimental epilepsy. (Neurobiology of Disease 76(2015) 87-97)

Caret imageSummary for non-specialists

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Chapter Spotlight:

Canadian Epilepsy Foundaton

Since its founding in 1977, the Canadian League Against Epilepsy has worked to enable Canadians affected by epilepsy to live a life that is not limited by their condition. In recent months, our chapter has launched a number of new committees and funding opportunities to increase our success at achieving our goals and mission.

Caret image Read about recent Canadian League activities


VIREPA Applications Now Open

Applications for the 2015-2016 Academic Year will be accepted from May 18 – August 3.

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ILAE eNewsletter

Free monthly email newsletter with brief highights of the ILAE's activities.

To subscribe, please provide your email address:

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Definition of Epilepsy 2014 - New definition and commentaries.

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