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NEWS

Report from the 10th Asian & Oceanian Epilepsy Congress

AOEC-2014

The 10th Asian & Oceanian Epilepsy Congress was held in Singapore August 7 - 10, 2014. The Congress was attended by over 1,300 delegates from 48 countries. The programme covered a broad range of topics selected from recommendations across the region and featured eminent speakers from the region and around the world. A total of 400 abstracts were submitted from centres across Asia and Oceania and from as far as Russia and USA on subjects ranging from cutting-edge basic science to critical community and epidemiological work. Many opportunities for discussion and networking were made, friendships renewed and new acquaintances made.

AOEC 2014
Opening address by Dr Lim Shih Hui, President, Singapore
Epilepsy Society
ECE 2014
Helen Cross, Ingrid Sheffer,
Samuel Wiebe and
Sam Bercovic
ECE 2014
Session chairs came
from around the world

Caret image Full report and more photos

News from ILAE

Epilepsy Regional Teaching Course, Kinshasa

Kinshasa course 2014 participants

The Congolese League Against Epilepsy (LICOCE) held an Epilepsy Regional Teaching Courses from September 6-11 in Kinshasa. Participants came from Burundi, Cameroon, Senegal, Benin and Morocco as well as Kinshasa and the DRC. This workshop was financially supported by the ILAE through its Commission on African Affairs (CAA) and the African Regional Committee (ARC) of The International Brain Research Organization (IBRO), and was the first collaborative experience between ILAE and IBRO in the Democratic Republic of the Congo.


Ice Bucket Challenge

Ice Bucket Challenge

ILAE and IBE Presidents' Ice Bucket Challenge

ILAE President Emilio Perucca and IBE President Thanos Covanis have joined together to urge all to:

  • learn more about epilepsy
  • fight discrimination
  • advocate for better epilepsy care
  • support epilepsy research and
  • celebrate the first International Epilepsy Day the second Monday in February, 2015

View Video

Caret imageMore news from ILAE

News Around the World
Yukio Fukuyama

Farewell: Yukio Fukuyama

It is with great sadness that we announce the death of Professor Yukio Fukuyama, a true pioneer in the field of pediatric neurology who chaired the Department of Pediatrics at Tokyo Women’s Medical University, for a quarter of a century, teaching and mentoring young doctors and leading us into the 21st century.


Ingrid Scheffer

Ingrid Scheffer receives Queen's Birthday honours

Ingrid Scheffer, past chair of the Classification and Terminology Commission of the ILAE, was appointed an Officer (AO) of the Order of Australia in the Queen’s Birthday Honours List for distinguished service to medicine as a clinician, academic and mentor, and for research into identifying epilepsy syndromes and genes.

Caret imageMore news around the world

Clinical Research News

Several studies now show great heterogeneity in mutations discovered by whole exome sequencing in epileptic encephalopathies

  • De novo KCNB1 mutations in epileptic encephalopathy (Annals of Neurology, volume 76, issue 4, pages 529-540)
  • Whole-exome sequencing broadens the phenotypic spectrum of rare pediatricepilepsy: a retrospective study (Clin Genet. 2014 Jul 21. doi: 10.1111/cge.12464)
  • De Novo Mutations in Synaptic Transmission Genes Including DNM1 Cause Epileptic Encephalopathies (Am J Hum Genet. 2014 Oct 2;95(4):360-70)
  • Mutations in SLC13A5 cause autosomal-recessive epileptic encephalopathy with seizure onset in the first days of life (Am J Hum Genet. 2014 Jul 3;95(1):113-20)

Impairment of ceramide synthesis causes a novel progressive myoclonus epilepsy

Alterations of sphingolipid metabolism are implicated in the pathogenesis of many neurodegenerative disorders. The authors demonstrated that the mutation decreases C18-ceramide levels. In addition, they showed that downregulation of CerS1 in a neuroblastoma cell line triggers ER stress response and induces proapoptotic pathways. (Annals of Neurology)

Caret imageMore clinical research news

Basic Science of Epilepsy News

Tau reduction prevents disease in a mouse model of Dravet syndrome

Tau ablation prevented the high mortality of Dravet mice and reduced the frequency of spontaneous and febrile seizures. It reduced interictal epileptic spikes in vivo and drug-induced epileptic activity in brain slices ex vivo. Tau ablation also prevented biochemical changes in the hippocampus indicative of epileptic activity and ameliorated abnormalities in learning and memory, nest building, and open field behaviors in Dravet mice. Deletion of only 1 Tau allele was sufficient to suppress epileptic activity and improve survival and nesting performance.


Epilepsia May 2014

Workshop on Neurobiology of Epilepsy appraisal:
New systemic imaging technologies to study the brain in experimental models of epilepsy

Successful application of functional neuroimaging of the whole brain in the animal laboratory now permits investigations during epileptogenesis and correlation with deep brain electroencephalography (EEG) activity. With the continuing development of these techniques and analytical methods, the potential for future translational research on epilepsy is enormous. Epilepsia. doi: 10.1111/epi.12642

Caret imageMore basic science news

 

Epileptic Disorders

Editor's Choice:
Can ACTH therapy improve the long-term outcome of drug-resistant frontal lobe epilepsy? Comments by Associate Editor Aristea S. Galanopoulou MD PhD

Caret image More about Epileptic Disorders

 

Chapter Spotlight:
Taiwan

YoungStar Training Program
Young-Star Epilepsy
Training Program

Taiwan Epilepsy Society (TES) was established in 1990 by a group of neurologists and pediatricians interested in treating patients with epilepsy. TES joined the International League Against Epilepsy (ILAsE) in 1993.

Caret image More about the Taiwan Epilepsy Society

 

Guidelines

Definition of Epilepsy 2014 - New definition and commentaries.

Caret imageRead all guidelines

 

ILAE eNewsletter

Free monthly email newsletter with brief highights of the ILAE's activities.

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