Commission on Classification and Terminology
Table 3: Electro-clinical syndromes and other epilepsies
Electro-clinical syndromes arranged by age at onset *
Neonatal period
Benign familial neonatal seizures (BFNS)
Early myoclonic encephalopathy (EME)
Ohtahara syndrome
Infancy
Migrating partial seizures of infancy
West syndrome
Myoclonic epilepsy in infancy (MEI)
Benign infantile seizures
Benign familial infantile seizures
Dravet syndrome
Myoclonic encephalopathy in nonprogressive disorders
Childhood
Febrile seizures plus (FS+) (can start in infancy)
Early onset benign childhood occipital epilepsy (Panayiotopoulos type)
Epilepsy with myoclonic atonic (previously astatic) seizures
Benign epilepsy with centrotemporal spikes (BECTS)
Autosomal-dominant nocturnal frontal lobe epilepsy (ADNFLE)
Late onset childhood occipital epilepsy (Gastaut type)
Epilepsy with myoclonic absences
Lennox-Gastaut syndrome
Epileptic encephalopathy with continuous spike-and-wave during sleep (CSWS)
including: Landau-Kleffner syndrome (LKS)
Childhood absence epilepsy (CAE)
Adolescence - Adult
Juvenile absence epilepsy (JAE)
Juvenile myoclonic epilepsy (JME)
Epilepsy with generalized tonic-clonic seizures alone
Progressive myoclonus epilepsies (PME)
Autosomal dominant partial epilepsy with auditory features (ADPEAF)
Other familial temporal lobe epilepsies
Less Specific Age Relationship *
Familial focal epilepsy with variable foci (childhood to adult)
Reflex epilepsies
Distinctive Constellations
Mesial temporal lobe epilepsy with hippocampal sclerosis (MTLE with HS)
Rasmussen syndrome
Gelastic seizures with hypothalamic hamartoma
Epilepsies that do not fit into any of these diagnostic categories can be distinguished first on the basis of the presence or absence of a known structural or metabolic condition (presumed cause) and then on the basis of the primary mode of seizure onset (generalized versus focal).
Epilepsies attributed to and organized by structural-metabolic causes
Malformations of Cortical development (hemimeganencephaly, hetertopias etc)
Neurocutaneous syndromes (Tuberous sclerosis complex, Sturge-Weber, etc)
Tumor
Infection
Trauma
Angioma
Peri-natal insults
Stroke
Etc.
Epilepsies of unknown cause
Conditions with epileptic seizures that are traditionally not diagnosed as a form of epilepsy per se.
Benign neonatal seizures (BNS)
Febrile seizures (FS)
*This arrangement does not reflect etiology.
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