Presidential Symposium title: Defining meaningful outcomes in the genomic era
Co-chairs: J Helen Cross (United Kingdom) & Francesca Sofia (Italy)

• What is a meaningful outcome – the lived experience - Amber Freed (USA)
• Setting the scene – are all outcomes relevant in different clinical settings? - James Mitchell (United Kingdom)
• Are all epilepsies the same – different measures for different epilepsies? - Scott Demarest (USA)
• Predicting outcome from epilepsy surgery - Colin Josephson (Canada)
• Will IGAP help to achieve meaningful outcomes? Action Amos (Malawi) 

Next generation networks to improve diagnosis and treatment in the epilepsies

Co-chairs: Dario Englot (USA) and Kate Davis (USA)

• Network predictors of response to medication and surgery - Simon Keller (United Kingdom)
• Neural network applications to imaging in epilepsy - Carrie McDonald (USA)
• Evoked stimulation responses to guide surgical decisions - Riki Matsumoto Japan)
• Network correlates of neuropsychiatric comorbidities - Aileen McGonigal (Australia)
• Implementing network analysis at the patient level: Barriers and minimum standards - Peter Taylor (United Kingdom)

 

Complex and Rare Epilepsies: The past, the present, and the future

Co-chairs: Kette Valente (Brazil) and J Helen Cross (United Kingdom)

• Living with a child with complex and rare epilepsy: Quality of life matters! - Francesca Sofia (Italy)
• Developmental and or Epileptic Encephalopathies: The need for an etiology-driven approach - Ingrid Scheffer (Australia)
• From catastrophic epilepsies to Developmental and/or Epileptic Encephalopathies: What is in a name? - Elaine Wirrell (USA)
• The unmet needs in the transition to adult care in DEEs and complex epilepsies: Leaving no one behind - Rima Nabbout (France)
• Treatment of DEE in low resource settings: The best and the possible - Edward Kija (Tanzania)
• Epilepsy Surgery in DEE: Can we predict outcomes? – Georgia Ramantani (Switzerland)

 

Newly diagnosed epilepsy: identification and intervention of neuropsychological sequelae

Co-chairs: Mary Lou Smith (Canada) and Gus Baker (United Kingdom)

• Patient-Centred Perspectives. Two presentations will capture the patient perspective, one from an adult with epilepsy and one from the parent/caregiver of a child with epilepsy. These presentations may be in person or by video, depending on the geographic location of the presenter and ability to attend the meeting.
• Neuropsychological problems and underlying mechanisms in children with newly diagnosed epilepsy. Jana Jones (USA)
• Neuropsychological problems and underlying mechanisms in adults with newly diagnosed epilepsy. Bruce Hermann (USA)
• Neuropsychological Interventions in newly diagnosed epilepsy: a review of the available evidence. Gus Baker (United Kingdom)
• Management of newly diagnosed epilepsy in both resource-plentiful and resource-limited settings: Sarah Wilson (Australia), Aimee Dollman (South Africa), and Urvashi Shah (India).
• Neuropsychological interventions: a pragmatic approach. Shivani Sharma (India)
• Panel Discussion / Questions and Answers

 

The chronobiology of epilepsy

Co-chairs: Jaideep Kapur (USA) and Jean Gotman (Canada)

• Risks and triggers to seizures – the patient perspective – Lorraine Lally (Ireland)
• Genetic and molecular mechanisms of seizure cycles - Cristina Reschke (Ireland)
• Multidien rhythms in the central nervous system - Maxime Baud (Switzerland)
• Sleep associated epileptic rhythms - Birgit Frauscher (Canada)
• Multidien rhythms in the autonomic nervous system – Rachel Stirling (Australia)

 

Evaluating drug resistance, surgical timing, and post-operative medications

Co-chairs: Nirmeen Kishk (Egypt) and Tatiana von Hertwig (Brazil)

• Case presentation – Nirmeen Kishk (Egypt)
• Definition and prediction of medication resistance – Patrick Kwan (Australia)
• Surgical decision trees – when should we consider surgery? – Guy McKhann (USA)
• Optimal timing of the post-operative medication wean – Laura Tassi (Italy)
• Case conclusion and Group Discussion - Nirmeen Kishk (Egypt)

Clinical diagnostic challenges in the genetic epilepsies and opportunities for precision treatment

Co-chairs: Susan Byrne (Ireland) and John Dunne (Australia)

• The lived experience of genetic testing for my epilepsy - Two local patients/families TBD – Ireland
• When should the medical professional consider a genetic test for epilepsy, what test(s) should they order, and what are the other considerations? - Ingo Helbig (USA)
• Looking under the bonnet of a genetic test for the epilepsies - Katherine Benson (Ireland)
• Precision therapies for epilepsy; what’s available and how well do they work? - Floor Jansen (Netherlands)

 

Plant based therapies for epilepsy: challenges and opportunities

Co-chairs: Kate Riney (Australia) and (KP Vinayan) India

• A patient experience - Yvonne Cahalane (Ireland)
• Why is there such a demand for plant-based therapies for epilepsy? - Elizabeth Thiele USA
• The cannabinoid story – what we have learned. - Cecilie Johannssen Landmark (Norway) and Finbar O’Callaghan (United Kingdom)
• Plant-based epilepsy treatments across cultures and world regions - Motlalepula Matsabisa (South Africa) and (KP Vinayan) India
• Potential novel agents and overcoming challenges in bringing to the market. - Siegward Elsas (Switzerland)

 

Climate change and epilepsy: everyone’s challenge

Co-chairs: Sanjay Sisodiya (United Kingdom) and David Henshall (Ireland)

• Climate change and human health: the big picture - Marina Romanelllo (United Kingdom)
• Climate change and neuronal networks: resilience? - Eve Marder (USA)
• Climate change and epilepsy: the lived experience - Galia Wilson (United Kingdom)
• Climate change and epilepsy: the lived experience - Priyanka Madaan hosting video of a person with epilepsy India
• Climate change and epilepsy: the lived experience - Bernadetter Macrohon hosting a video of a person with epilepsy Philippines
• Climate change: the global action agenda - Alla Guekht (Russian Federation)

 

Paediatric epilepsy surgery: rethinking concepts and reimagining possibilities

Co-chairs: Georgia Ramantani (Switzerland) and Roberto Caraballo (Argentina)

• Current international practice in pediatric epilepsy surgery - Sarah Ferrand-Sorbets (France)
• Offering pediatric epilepsy surgery before pharmacoresistance - Kees Braun (Netherlands)
• Offering palliative resective surgery in pediatrics - Scott Perry (USA)
• Redefining pediatric epilepsy surgery outcomes - Mary Lou Smith (Canada)

 

Identifying and managing neurobehavioral comorbidities in children with epilepsy -Can we bridge the gap?

Co-chairs: Colin Joseph Reily (Sweden) and Francesca Sofia (Italy)

• When the evidence is so clear these conditions go hand in hand, how can those departments not talk to one another - Emma Dalrymple (United Kingdom)
• They do their best to help with his epilepsy ..the rest almost nothing” - Josefine Soto Jansson (Sweden)
• Screening for neurobehavioural difficulties in children with epilepsy – what are the challenges? - Kirsty Donald (South Africa)
• What are the options for treating for treating neuropsychiatric difficulties in children with epilepsy? - Jay Salpekar (USA)

 

A multi-layered and integrative classification scheme for FCD: the ILAE consensus classification update 2022

Co-chairs: Ingmar Blümcke (Germany) and Imad Najm (USA)

• Layer 1: Histopathology subtypes of FCD according to the classification update 2022 - Ingmar Blümcke (Germany)
• Layer 2: When and how to apply neurogenetic testing in surgical tissue specimens of FCD -Dennis Lal (USA)
• Layer 3: How to report and integrate neuroimaging findings of FCD - Fernando Cendes (Brazil)
• Why, how and when to build an integrated diagnosis of FCD - Imad Najm (USA)

 

Innovation Gaps in Epilepsy- Shortening Timelines and Improving Access to New Treatments for Epilepsy

Co-chairs: Archana Patel (USA) and Ghaieb Aljandeel (Iraq)

• Gaps from ASM Development to Accessibility Across the Globe - Timothy Welty (USA)
• Innovation Landscape in a developing region – Satish Jain (India)
• Relevance of Epilepsy Treatment Innovation in Resource-Constrained Regions - Charles Hammond (Ghana)
• Efforts of the ILAE Access to Treatment Task Force: Initial steps in identifying key aspects of the problems and where to go from here - Thierry Darcis (United Kingdom)

 

The ILAE syndrome classification as a roadmap for epilepsy-associated comorbidities

Co-chairs: Stéphane Auvin (France) and Michael Sperling (USA)

• Autism Spectrum Disorder in Developmental and/or Epileptic Encephalopathies: Under or Overrated? - Colin Reilly (United Kingdom)
• Delineating behavioral and cognitive phenotypes in juvenile myoclonic epilepsy: Are we missing the forest for the trees? - Kette Valente (Brazil)
• Epilepsy syndromes with onset at a variable age: Red Flags for Behavioral and Psychiatry Comorbidities in Focal Epilepsies - Marco Mula (UK)
• Using the 2022 ILAE syndrome classification as a roadmap to think about comorbidities screening and diagnosis - Stéphane Auvin (France)

 

Reducing the treatment gap and mitigating economic implications in pediatric epilepsy

Co-chairs: Symon Kariuki  (Kenya) and Jo Wilmhurst (South Africa)

• Treatment gap in pediatric epilepsy: The size, causes and consequences of the problem - Sebastian Ortiz
• Structured interventions in a busy clinical setting - Symon Kariuki (Kenya)
• Education and health literacy: Building a training program for people with epilepsy and their families – Mary Secco (Canada) 
• Domesticating the IGAP’s 90-80-70 cascade target for the epilepsy treatment gap in low- and middle-income settings - Action Amos (Africa)

 

Creating small lesions to treat epilepsy

Co-chairs: Michael Sperling (USA) and Samuel Wiebe (Canada)

• Balancing seizure outcome and invasiveness in epilepsy surgery – John Rolston (USA)
• Thermal ablation for epilepsy - Michael Sperling (USA)
• Radiofrequency ablation to treat lesions and networks in epilepsy - Helene Catenoix (France)
• Focused ultrasound: lesioning and neuromodulation in epilepsy - Hsiang-Yu Yu (Taiwan)

 

"I’m terrified of my epilepsy”: Managing the challenge of anxiety in epilepsy patients

Co-chairs: Milena Gandy (Australia) and Rosa Michaelis (Germany)

• Patient perspectives: We will hear from both a paediatric and adult patient about their experience of living with epilepsy and anxiety. - Heidi Munger Clary, Gaston Baslet, and Sophie Bennett
• Development and maintenance of anxiety in epilepsy: the latest science on neurobiological and psychosocial perspectives - Coraline Hingray (France) and Milena Gandy (Australia)
• Best practice and practical tips for the diagnosis and management of anxiety across the lifespan. - Sophie Bennett and Gaston Baslet
• Panel Discussion: How well we are meeting the challenge of identifying and managing anxiety in epilepsy and further research needed. - Providence Umuziga (Rwanda)

 

Imaging, electrophysiology, and genetics: At the interface of epilepsy inheritance risks and lifespan plasticity

Co-chairs: Britta Wandschneider (UK) and Boris Bernhardt (Canada)

• Bringing imaging, genetics and other modalities together: some examples - Sanjay Sisodiya (United Kingdom)
• Imaging-transcriptomic signatures in focal and generalized epilepsies - Sara Lariviere (USA)
• Heritability of cognitive and imaging traits in idiopathic generalized epilepsy - Lorenzo Caciagli (USA)
• Heritability of MEG/EEG phenotypes among patients with generalized epilepsy and their siblings - Christina Stier (Germany)
• White matter: Genes, epilepsy and cognition - Luis Concha (Mexico)

 

Multi-omics in acquired epilepsies: beyond genes and transcripts

Co-chairs: Pablo Casillas-Espinosa (Mexico/Australia) and Edward Bertram (USA)

• Proteomics and metabolomic dysregulation in models of acquired epilepsies - Pablo Casillas-Espinosa (Mexico/Australia)
• Commonalities between multi-omics studies in basic and clinical epilepsy, do they translate?- Iscia Lopes-Cendes (Brazil)
• Systems biology integration to identify novel disease-modifying targets in epilepsy- Jeffrey Loeb (USA)
• Should we treat pathways rather than single molecular targets in acquired epilepsies?- Heidrun Potschka (Germany)

 

Autoimmune epilepsy and immune-mediated epilepsy - two sides of the same coin ?

Co-chairs: Derrick Chan (Singapore) and Annamaria Vezzani (Italy)

• Case presentation - Adeline Ngoh (Singapore)
• The immune foundations of epilepsy - Annamaria Vezzani (Italy)
• The immune crossroads of the brain - what lessons can epilepsy and multiple sclerosis teach us - Francisco Quintana (USA)
• Autoimmune encephalitis, anti-neuronal antibodies and seizures - no smoke without fire - Angela Vincent (United Kingdom)
• Looking back, moving forward - possible directions for future research in immune dysfunction and inflammation in epilepsy - Derrick Chan (Singapore)

 

Innovations in the prevention and treatment of epilepsy in tuberous sclerosis complex

Co-chairs:  Mark Keezer (Canada) and Phillippe Major (Switzerland)

• The experience of one mother and her child with TSC and epilepsy - Cathy Evanochko (Canada)
• Disease modifying therapies in TSC - Sergiusz Jozwiak (Poland)
• Alternative antiseizure medications in TSC - Nicola Specchio (Italy)
• Neuroinflammation and epilepsy severity in TSC - Catherine Larochelle (Canada)
• Candidate selection for epilepsy surgery in TSC. – Simon Harvey (Australia)

 

The multifarious mTOR signaling pathway in the epilepsies

Co-chairs:  Steve Danzer (USA) and Elenora Aronica (Netherlands)

• Brain somatic mutations in mTOR pathway genes leading to focal cortical dysplasia – Jeong Ho Lee (South Korea)
• Modelling somatic mosaicism and targeted therapies – Stéphanie Baulac (France)
• Downstream and parallel targets of mTOR signalling for epilepsy treatment – Lena Nguyen (USA)
• Differential roles of mTORC1 and mTORC2 in epilepsy development – Steve Danzer (USA)
• mTOR signalling and neuroinflammation in epilepsy -- Eleonora Aronica (Netherlands)

 

Moving exercise in epilepsy forward – steps towards success
Co-chairs:  Jane Allendorfer (USA) and Elinor Ben-Menachem (Sweden)

• Experimental findings for exercise effects in epilepsy - Ricardo M. Arida (Brazil)
• Physical fitness and activitiy levels in children and adults with epilepsy - Elinor Ben-Menachem (Sweden)
• Optimizing exercise effects for people with epilepsy - Halley Alexander (USA)
• Improving exercise engagement and trial participation for people with epilepsy – considering social determinants of health -Jane Allendorfer (USA)
• Relationship between exercise and metabolic syndrome in epilepsy - Sudhindra Vooturi (India)

Decision support tools in epilepsy: are we there yet?

Co-chairs:  Karl Martin Klein (Canada) and Colin Josephson (Canada)

• Precision medicine in epilepsy: from rare monogenic to common epilepsies -Karl Martin Klein (Canada)
• Engaging patients to improve seizure forecasting and deploy wearable devices – Philippa Karoly (Australia)
• Strategies for data collection in the future - Spiros Denaxas (United Kingdom)
• Clinical prediction tools in epilepsy: current models outperform physicians and should be widely deployed - Carolina Ferreira Atuesta (USA)
• Clinical prediction tools in epilepsy: from premonition to certainty - Colin Josephson (Canada)

 

Hypothalamic hamartoma – evolving understanding of evolution and treatment of an epileptic syndrome

Co-chairs:  Kathrin Wagner (Germany) and J Helen Cross (United Kingdom)

• Genetic and clinical workup for HH – what do we need? - Samuel Berkovic (Australia)
• Cognitive and behavioral development in HH – what do we know? - Kathrin Wagner (Germany)
• To treat or not to treat: the role of gelastic and other seizure types - Julia Jacobs (Canada)
• New treatments for unilaterally and bilaterally attached hamartomas - Hiroshi Shirozu (Japan)

 

Neonatal Seizures and Epilepsy - From the past to the future: Why we still have controversies?

Co- chairs: Nicholas Abend (USA) and Magda Lahorgue (Brazil)

• New ILAE Classification of Neonatal Seizures- Ronit Pressler (United Kingdom)
• Neonatal EEG Monitoring Rationale and Approach- Nicholas Abend  (USA)
• Diagnosing Neonatal Seizures Earlier and More Efficiently- Geraldine Boylan (Ireland)
• New Definitions and Guidelines for Neonatal Status Epilepticus- Magda Lahorgue Nunes (Brazil)
• New ILAE Neonatal Seizure Treatment Guidelines - Hans Hartmann (Germany)

 

Digital systems help in diagnosis and treatment of epilepsy?

Co-chairs: Yvonne Weber (Germany) and Sándor Beniczky (Denmark)

• Seizure detection systems are needed -Stefan Wolking (Germany)
• Seizure detection systems can produce mainly false positive and negative alarms - Sándor Beniczky (Denmark)
• Clinical decision systems will improve daily life - Katya Lin (Brazil)
• Clinical decision systems are not suitable for daily life - Jacqueline French (USA)

 

Acute symptomatic seizures: what is benign, what needs treatment?

Co-chairs: Marian Galovic (Switzerland) and Francesco Brigo (Italy)

• Mechanisms of acute seizures following brain insults - Asla Pitkänen (Finland)
• Acute symptomatic seizures in cerebrovascular disease - Marian Galovic (Switzerland)
• Management of acute symptomatic seizures in the ICU - Vineet Punia (USA)
• To treat or not treat: interactive case based discussion on acute symptomatic seizures - Francesco Brigo (Italy)

 

Beyond Ketogenic Diet: What metabolic system should be targeted for clinical intervention in epilepsy
Co-chairs: Jennifer Dowling (Ireland) and Detlev Boison (USA)

Format: Debate: What metabolic pathway should be prioritized for clinical implementation?

• Introduction: Ketogenic diet and beyond: what is on the horizon? Manisha Patel
• Patient Representative - Mike Dancer (United Kingdom)
• Metabolic pathways to be debated.:
  • Adenosine - Detlev Boison (USA)
  • Glucose - Chris Dulla (USA)
  • Energetics and Lipids - Manisha Patel (USA)
  • Medium Chain Triglycerides - Karin Borges (Australia)

• What systems are in play? - Jennifer Dowling (Ireland)
• What are the tools for drug discovery? - Mark Cunningham (Ireland)
• Panel discussion and debate

An Irish challenge – complex cases for the experts

Chair: Peter Widdess-Walsh (Ireland)

In Irish tradition, persons with complex epilepsy will be presented, and interviewed by a panel of experts from Ireland and around the world. As the experts discuss and reveal the history, semiology, and neurophysiology, we will learn about these complex epilepsies and their effect on the person’s life.

Interview with a person with epilepsy - Challenging cases for the experts

• Norman Delanty (Ireland)
• Terry O’Brien (Australia)
• Lara Jehi (USA)
• Mary King (Ireland)
• André Palmini (Brazil)

 

Full-day Teaching Course: Neuroimaging in epilepsy - what the clinician should know

• Introduction to neuroimaging in epilepsy. – Anna Elisabetta Vaudano (Italy)
• MRI physics, sequence names, and MRI epilepsy protocol. – Godwin Ogbole (Nigeria)
• Common epileptic pathologies: temporal epilepsy. – Fernando Cendes (Brazil)
• Common epileptic pathologies: extratemporal lobe epilepsy.
• Hands-on session – Stefan Rampp (Germany)
• MRI-negative epilepsy. What are the next steps?
• Other neuroimaging modalities: PET, SPECT, etc.
• fMRI (task-based) & EEG-Fmri – Paolo Federico (Canada)
• Diffusion imaging, presurgical image fusion – Luis Concho (Mexico)
• Hands-on session - Stefan Rampp (Germany)
• Group discussion/feedback

 

Half-day Teaching Course: Is this epilepsy? If not, what is it?

Short description:

This session will address differential diagnosis: epileptic seizures vs. non-epileptic paroxysmal events. How to extract relevant clinical information from history and from video recordings.

Co-chairs: Michael Sperling (USA) & Elza Márcia Yacubian (Brazil)

• Markus Reuber (United Kingdom)
• Michael Sperling (USA)
• Lino Nobili (Italy)
• Elza Márcia Yacubian (Brazil)

 

Half-day Teaching Course: Syndrome Classification

Short description:

This interactive session will use a case-based approach to new ILAE Syndrome classification.

Co-chairs: Elaine Wirrell (USA) & Sameer M. Zuberi (UK)

• Introduction to Syndrome Definition and Methodology - Elaine Wirrell (USA) & Sameer M. Zuberi (UK)
• Epilepsy syndromes with onset in the Neonatal Period and Infancy - Sameer M. Zuberi (UK)
• Epilepsy syndromes with onset in Childhood - Elaine Wirrell (USA)
• Epilepsy Syndromes with Onset at a Variable Age - Kate Riney (Australia)
• Idiopathic Generalized Epilepsy Syndromes - Edouard Hirsch (France)

 

Half-day Teaching Course: Let´s read EEGs together!

Short description:

In the first part, the following theoretical blocks will be addressed: how to localize an EEG abnormality, interictal patterns, ictal patterns, normal variants and artefacts. In the second part, the tutors will read representative EEG samples together with the students.

Chair: Sándor Beniczky (Denmark)

• Systematic approach to clinical EEG reading - Sándor Beniczky (Denmark)
• EEG in epilepsy syndromes: the context matters - Dana Craiu (Romania)
• Normal variants and artefacts - Fabio Nascimento (USA)

 

Half-day Teaching Course: No response to first ASMs. What next?

Short description:

This session will address the options after the first and second failed ASM.

Co-chairs: Torbjörn Tomson (Sweden) & Jacqueline French (USA)

• Resistant or pseudo-resistant: Things to consider before changing ASM - Torbjörn Tomson (Sweden)
• Failure of first ASM: Is every drug the same? - Jacqueline French (USA)
• Debate: Switch or add after first failed ASM?  - For switch Jacqueline French, for add Anthony Marson 
• 2^nd ASM failure: which ASM to add and how? - Anthony Marson (United Kingdom)
• Non-pharmacological alternatives to a 3^rdASM - Kristl Vonck (Belgium)

 

Half-day Teaching Course: Epilepsy surgery: learn from cases!

Short description:

This session will describe the challenges of presurgical evaluation, using case-based learning.

Co-chairs: Ivan Rektor (Czech Republic) & Çiğdem Özkara (Turkey)

• Ivan Rektor (Czech Republic)
• Philippe Kahane (France)
• Çiğdem Özkara (Turkey)
• Philippe Ryvlin (Switzerland)

 

Half-day Teaching Course: Status epilepticus

Short description:

This session will provide an overview of challenges diagnosing classifying and treating a highly dynamic condition, using case-based learning.

Co-chairs: Eugen Trinka (Austria) & Simon Shorvon (United Kingdom)

Classification, Epidemiology and Causes - Eugen Trinka (Austria)

Diagnosis: EEG and MRI  - Giada Giovanni (Italy)

Treatment of early status and established status - Simon Shorvon (United Kingdom)

Treatment of Refractory and super-refractory SE – Alexandra Astner-Rohracher (Austria)

 

Half-day Teaching Course: Genetic testing: whom, when and what to test

Short description:

This session will give an overview on the clinical use of genetic testing in patients with epilepsy.

Chair: Guido Rubboli (Denmark)

• Guido Rubboli (Denmark)
• Renzo Guerrini (Italy)
• Rima Nabbout (France)
• Amy McTague (United Kingdom)

 

Half-day Teaching Course: Patient and Public Involvement in Epilepsy Research

Short description:

Co-chairs: Reetta Kälviäinen (Finland) & Donna Walsh (Ireland)

• Definitions, role and impact of PPI in current epilepsy research - Gianpiero Cavalleri (Ireland)
• PPI for brain research in low- and middle-income countries - Iracema Leroi (Ireland)
• PPI solutions for rare and complex epilepsy - Reetta Kälviäinen + video interviews of patients (Finland)
• IBE-INVOLVE project building the knowledge and skills for PPI in epilepsy - Claire Nolan (United Kingdom)

 

Half-day Teaching Course: Which ASM to start with? When to stop?

Short description:

This session will address the choice of first ASM and discuss the factors that are important for making this decision. In addition, the speakers will discuss the way the ASMs are introduced, when and how to stop them.

Chair: Emilio Perucca (Australia) and Sarah Eyal (Israel)

• Choosing the most appropriate ASM in newly diagnosed - Martin Brodie (United Kingdom)
• Tailoring treatment choices to account for comorbidities and potential drug interactions - Sara Eyal (Israel)
• What next when the first treatment fails?  - Jakob Christensen (Denmark)
• Stopping an ASM in seizure-free individuals – risks versus benefits - Emilio Perucca (Australia)

VIREPA Basic & Advanced EEG

• Elena Gardella (Denmark)
• Antonio Valentin (United Kingdom)

 

VIREPA Paediatric EEG & VIREPA MRI

• Monika Eisermann (France)
• Stefan Rampp (Germany)

 

Advanced EEG: source imaging – part 1 (Theory)

• Sandor Beniczky (Denmark)
• Stefan Rampp (Germany)

 

Advanced EEG: source imaging – part 2 (Hands-on)

• Sandor Beniczky (Denmark)
• Stefan Rampp (Germany)

 

Video session – paediatric

• Ronit Pressler (United Kingdom)
• Nicola Specchio (Italy)
• Alexis Arzimanoglou (France)

 

Video session – adult

• Guido Rubboli (Denmark)
• Matthew Walker (United Kingdom)
• Laura Tassi (Italy)

 

Immunity, inflammation and epilepsy

Chair:  Christian Bien (Germany)

• The immunology underlying autoimmune epilepsies – Jan Bauer (Austria)
• Epileptogenic mechanisms of human autoantibodies - Christian Geis (Germany)
• Management of patients with suspected autoimmune epilepsy - Christian Bien (Germany)
• Autoimmune epilepsy in paediatric patients - Sukhvir Wright (United Kingdom)

 

Epileptic encephalopathies

• Federico Vigevano (Italy)
• Alexis Arzimanoglou (France)
• J Helen Cross (United Kingdom)

 

The relevance of animals’ models in epilepsy research and drug discovery

Co-chairs: Cristina Ruedell Reschke (Ireland) and David Henshall (Ireland)

• Animal models of seizures and acquired epilepsies - Cristina Ruedell Reschke (Ireland)
• Models of genetically determined epilepsies - David Henshall (Ireland)
• The use of animal models in drug screening - Pablo Casillas-Espinosa (Australia) and Vincenzo Mara, Belgium
• Pre-clinical evaluation of gene therapy for drug-refractory epilepsies - Gabriele Lignani (United Kingdom) and Stephanie Baulac (France)

 

Why do we need to record EEG in animal models?

Co-chairs: Julia Jacobs (Canada) and Premysl Jiruska (Czech Republic)

• The role of EEG in animal studies and pre-clinical testing - Premysl Jiruska (Czech Republic)
• Methods of EEG recording – from standard video-EEG to advanced approaches - Christos Lisgaras (USA)
• Electroclinical features of genetic epilepsy models - Massimo Mantegazza (France) and Simona Balestrini (Italy)
• EEG as a tool to dissect epileptic networks - Mark Cunningham (Ireland) and Julia Jacobs (Canada)

Adult Epileptology

1. Resilience and epilepsy: impact on psychosocial factors and stigma - Mario Tombini (Italy)
2. An internationally derived Core Outcome Set for Adult Epilepsy Treatment Trials: The EPSET Project - James W. Mitchell (United Kingdom)
3. Impact of Fenfluramine on Drop Seizure Frequency in Adults or Dose-Capped Patients With Lennox-Gastaut Syndrome: Comparative Analysis of Clinical Trial Data - Ingrid E. Scheffer (Australia)
4. Predictors of long-term epilepsy in acute subarachnoid hemorrhage: clinical features, neuroimaging and EEG factors - Daniel Campos-Fernández (Spain)
5. Risk of New-onset Stroke in Older People with Epilepsy without Prior History of Stroke: A Study of the Canadian Longitudinal Study of Aging (CLSA) - Jimmy Li (Canada)

 

Basic Science 1

1. Brain extracellular matrix alters local ion concentrations and responses to injury - Kieran Normoyle (United States)
2. Global disruption of RNA (m6A) methylation patterns contribute to the formation and maintenance of hyperexcitable brain networks - Gary Brennan (Ireland)
3. Transplantation of human stem cell-derived inhibitory neurons suppress recurrent seizures - Merab Kokaia (Sweden)
4. Circadian timing of limbic seizures in the epileptic mouse - Kristina Slabeva (Switzerland)

 

Basic Science 2

1. The synergistic relationship between Alzheimer’s Disease and recurrent seizures is mediated by dysregulated gliosis and reactivation of immediate-early genes - Nigel Jones (Australia)
2. Single cell transcriptomics and systems immunology approaches identifies pro-inflammatory immune mechanisms and potential drug targets in refractory epilepsy - Pavanish Kumar (Singapore)
3. Changes in hippocampal neurotransmission and neuroinflammation caused by air pollution can predispose rats to epileptic seizures. - Maria José da Silva Fernandes (Brazil)
4. Circulating microRNA profiles distinguish epilepsy from seizure mimics in a hospital emergency department setting. - Claire Behan (Ireland)
5. Mutated neurons in mouse model of focal cortical dysplasia display different firing profile than healthy pyramidal cells. - Minh Thao Nguyenova (Czech Republic)

 

Clinical Neurophysiology

1. Generalized spike-waves in idiopathic generalized epilepsies: does their frequency matter? - Mohsen Farazdaghi (Iran, Islamic Republic of)
2. Propagating source reconstructions from stereo-EEG identify new surgical targets in patients with inconclusive initial evaluation or failed surgery - Brandon Thio (United States)
3. Home recording of electrographic typical absence seizures with the Sensor Dot: performance and patient feedback - Lauren Swinnen (Belgium)
4. Permutation entropy derived parameters to estimate the epileptogenic zone network - Ionut-Flavius Bratu (France)
5. Impact of ambulatory EEG on the assessment of epileptic patients in resource-limited Latin-American populations - Francisco Javier Taveras Almonte (Dominican Republic)

 

Drug Therapy 1

1. Perampanel for Treatment of Focal and Generalised Epilepsy in Everyday Clinical Practice: Evidence from PERMIT 2 - Eugen Trinka (Austria)
2. A Randomized, Double-Blind, Placebo-Controlled, Phase 3 Study to Evaluate the Safety and Efficacy of XEN1101 as an Adjunctive Therapy in the Treatment of Primary Generalized Tonic-Clonic Seizures - Cynthia Harden (Canada)
3. Faster Time to Treatment of Seizure Clusters With Diazepam Nasal Spray Is Associated With Faster Cessation of Clusters: A Post Hoc Analysis - Enrique Carrazana (United States)
4. 12-Month Effectiveness and Tolerability of Brivaracetam in Patients With Epilepsy Stratified by Etiology at Baseline in the Real-World: Subgroup Data From the International EXPERIENCE Pooled Analysis - Adam Strzelczyk (Germany)
5. Design of Two Parallel Randomized, Double-Blind, Placebo-Controlled Phase 3 Studies to Evaluate the Safety and Efficacy of XEN1101 as Adjunctive Therapy in the Treatment of Focal Onset Epilepsy - Christopher Kenney (Canada)

 

Drug Therapy 2

1. What do 90-99% responder rates mean in patients treated with cenobamate: results from the open label extension (OLE) of study C017 - Jose M. Serratosa (Spain)
2. Efficacy and safety of vitamin D supplementation on seizure control in drug resistant epilepsy and its correlation with vitamin D receptor expression: A randomize controlled trial - Soumya Sucharita Pattnaik (India)
3. Gabapentin use during pregnancy and adverse neonatal birth outcomes: a population-based cohort study - Alekhya Lavu (Canada)
4. Anticonvulsant effects of the natural products magnolol and amorfrutin-2 in the Scn1a+/- mouse model of Dravet syndrome. - Ka Lai Yip (Australia)
5. Poor seizure outcome in patients with genetic generalized epilepsies undergoing a switch from valproate to other antiseizure medications - Laura Maria Guilhoto (Brazil)

 

Epilepsy Surgery

1. Are Healthy Brain Regions Tonically Inhibiting Seizure Onset Zones? The Interictal Suppression Hypothesis in Focal Epilepsy - Graham Johnson (United States)
2. Predictors of seizure freedom/drug freedom after epilepsy surgery in a pediatric series - Concetta Luisi (Italy)
3. Determinants of functional outcome after pediatric hemispherotomy - Georgia Ramantani (Switzerland)
4. Timing for starting antiseizure medication withdrawal after epilepsy surgery in adults - Carolina Ferreira-Atuesta (United Kingdom)
5. All-cause mortality continues to decrease after successful resective epilepsy surgery – a long-term population-based study - Cecilia Granthon (Sweden)

 

Epilepsy Surgery

1. A Spatial Perturbation Framework to Validate Intracranial Electroencephalogram Implantation of the Epileptogenic Zone - Kassem Jaber (Canada)
2. Personalized whole brain network modelling on virtual epilepsy surgery - Huifang Wang (France)
3. Pathways to epilepsy surgery in a cohort of 85 children with epilepsy associated with Tuberous Sclerosis Complex. - Lucas Gauer (France)
4. Clinical yields of ultra-long sub-cutaneous EEG monitoring in drug-resistant focal epilepsies - Guido Rubboli (Denmark)
5. Clinical Information informs automated Detection of Focal Cortical Dysplasia - Lennart Walger (Germany)

 

Genetics 1

1. The genetic landscape across more than 1000 surgically accessible epileptogenic human brain lesions - Dennis Lal (United States)
2. Pathogenic GABRA3 variants lead to dominant or recessive X-linked disorders depending on functional outcomes - Katrine M. Johannesen (Denmark)
3. Gain-of-function and loss-of-function GRIA3 variants lead to distinct neurodevelomental phenotypes - Allan Bayat (Denmark)
4. Long-term evolution of SCN8A-related conditions: focus on transition age - Caterina Ancora (Italy)
5. HCFC1 variants in the proteolysis domain are associated with X-linked idiopathic focal epilepsy: exploring the underlying mechanism - Na He (China)

 

Genetics 2

1. Clinical phenotypes of patients with GABRG2 loss-of-function and gain-of-function variants. - Alessandra Rossi (Denmark)
2. Developmental and epileptic encephalopathies associated with gain-of-function GABRB3 variants are more severe than those with loss-of-function. - Philip K. Ahring (Australia)
3. Somatic Mutations as a Cause of Drug-Resistant Epilepsy Including Hippocampal Sclerosis - Michael Doyle (Ireland)
4. Natural history and adult phenotype of SYNGAP1-DEE. ​ - Quratulain Ali (Canada)
5. Variants in SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy: genome wide association study - Deb K. Pal (United Kingdom)
6. Analysis of more than 90,000 diagnostic tests in people with epilepsy identifies the age of seizure onset-specific epilepsy-associated genes – Alina Ivaniuk (USA)

 

Neuroimaging

1. Atrophy in subcortical brain structures in newly diagnosed focal epilepsy is associated with alterations in white matter connectivity and neuropsychology. - Christophe de Bezenac (United Kingdom)
2. Localization of temporal lobe epilepsy networks from individualized atrophy patterns - Sara Larivière (United States)
3. Anti-seizure medications may not influence brain morphometry in mesial temporal lobe epilepsy: a prospective MRI study - Ilaria Sammarra (Italy)
4. Structural Correlates of Drug Resistance in Juvenile Myoclonic Epilepsy - Bernardo Crespo Pimentel (Austria)
5. Segmenting Focal Cortical Dysplasias using Graph Neural Networks: a MELD study - Konrad Wagstyl (United Kingdom)

 

Neuropsychology

1. Neuropsychological outcomes following stereo-EEG radiofrequency thermocoagulation - Emily Cockle (Australia)
2. Developmental trajectories in Developmental and Epileptic Encephalopathies - Tommaso Lo Barco (Italy)
3. Abnormal metabolic patterns revealed by 1H MR spectroscopy associate with cognitive findings in progressive myoclonus type 1 (EPM1) patients - Jelena Hyppönen (Finland)
4. Prevalence and risk factors for anxiety and depression in adult patients with epilepsy: A multicenter survey-based study - Jinmei Li (China)
5. The wellbeing neuro course: A randomized controlled trial of an internet-delivered transdiagnostic psychological intervention for adults with epilepsy and other neurological disorders - Milena Gandy (Australia)

 

Paediatric Epileptology

1. Contralesional epileptiform activity in Rasmussen’s Encephalitis is associated with early disease onset, cortical and microstructural alterations in the contralateral hemisphere, cognitive decline, and unfavorable outcome after hemispherotomy - Tobias Bauer (Germany)
2. Quantitative MRI correlates of epilepsy and cognitive deficits in school-age children and young adults with Sturge-Weber syndrome - Csaba Juhasz (United States)
3. The ENVISION Study, an International, Prospective Natural History Study in Young Children with SCN1A+ Dravet Syndrome, 18 Month Follow-up - Susana Boronat (Spain)
4. Establishing PROMs in medication management of rare genetic epilepsies: What are the best medications in 228 SYNGAP1 patients? - Kirsten Eschermann (Austria)
5. Ketogenic Diet in Infants with Epilepsy (KIWE): a Randomised Controlled Trial - Natasha Schoeler (United Kingdom)

 

Social Issues and Nursing

1. Adapting a Self-management Program for Adolescents with Epilepsy - Erica Johnson (United States)
2. Pre-Surgical Preparation and Post-Surgery Recovery: Suggestions for Patient-Provider Partnerships - Ben McVicker (Canada)
3. Dance, equine-assisted therapy and social participation of people with epilepsy - Lavinia Teixeira-Machado (Brazil)
4. Improving Acute Seizure Management through an Interprofessional Education Program - George Savvides (United States)
5. Single Centre Evaluation of a Consultant Nurse Led, ‘One-Stop’, First Seizure Clinic (FSC) - Phil Tittensor (United Kingdom)

 

Status Epilepticus

1. Cytokines in patients with New-Onset Refractory Status Epilepticus (NORSE) predict outcomes - Aurelie Hanin (United States)
2. Mortality and risk of epilepsy after acute symptomatic status epilepticus following ischemic stroke and an updated prognostic model (SeLECT 2.0) - Marian Galovic (Switzerland)
3. Prediction of long-term epilepsy after new-onset status epilepticus - Marc Rodrigo-Gisbert (Spain)
4. Machine Learning prediction of seizure recurrence after Status Epilepticus - Francesco Pasini (Italy)
5. Changes in synaptic dynamics underlies benzodiazepine resistance in paediatric status epilepticus - Tommaso Fedele (Switzerland)

 

Mixed

1. Does maternal genetic liability to folate deficiency influence the risk of antiseizure medication-associated language impairment and autistic traits in children of women with epilepsy? - Marte-Helene Bjork (Norway)
2. Visualizing the 2022 Classification of Epilepsy Syndromes: An Interactive Teaching Resource - Rima Nabbout (France)
3. Personalized therapeutic management of epilepsy patients with metabolic breath analysis - Kathrin Muesch (Switzerland)
4. Independent associations of incident epilepsy, enzyme-inducing, and non-enzyme-inducing antiseizure medications with the development of osteoporosis: a population-based analysis - Colin Josephson (Canada)
5. Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy (START) Clinical Trial - Hal Blumenfeld (United States)

 

Epilepsy Surgery Advances, Access, and Adaptability

Co-chairs: Dario Englot (USA) & Arthur Cukiert (Brazil)

Welcome and Introduction to Symposium Topics

1. Novel Surgical Approaches

• Combined Neuromodulation- Arthur Cukiert (Brazil)
• Surgical Options for Generalized Epilepsy – Sarah Bick (USA)
• New Advances in Disconnection Surgery - Taylor Abel (USA)

2. Epilepsy Surgery Access and Throughput

• Epilepsy Surgery Trends and Barriers - Nathalie Jette (USA)
• Access to Surgery in Developing Countries - Jorge Burneo (Canada)
• Building and Running a Large Surgical Program – Xiongfei Wang (China)

3. Case-Based Epilepsy Surgery

• Optimizing an Intracranial Implant in the Modern Era – Sarah Ferrand Sorbets (France)
• Advanced brain and vagal nerve stimulation programming approaches - Kristl Vonck (Belgium)
• Novel Imaging Approaches for Challenging Cases - Christian Dorfer (Austria)
• Optimizing Location and Extent of Resection in TLE Surgery - Mario Alonso-Vanegas (Mexico)
• Discussion and Conclusions

New Frontiers in Blood brain barrier regulation and epilepsy

Co-chairs: David Henshall (Ireland) and Matthew Campbell (Ireland)

• Blood-brain barrier pathology in epilepsy: from bench to bedside - Alon Friedman (Canada)
• BBB restoration through induction of claudin-5 prevents seizures - Matthew Campbell (Ireland)
• Pre-clinical models and therapeutics regulating the BBB - Merav Shamir (Israel)
• BBB receptors and epilepsy - Chaitali Ghosh (USA)
• Mechanosensor channel Piezo1 at the neurovascular unit during seizures and immune modulations - Nicola Marchi (France)

Epilepsy Nursing Practice: Identifying Common Themes and Innovative Solutions to address the Treatment Gap

Co-chairs: Karen Legg (Canada) and TBC

 

1: Nursing initiatives for Improving Access to Service:

Chair: Karen Legg (Canada)

• The lived experience. A personal journey with epilepsy - Alison Kukla (USA)
• Use of technology in resource limited countries- Jane von Gaudecker (USA)
• Project ECHO telementoring program – Patricia Osborne-Shafer
• Nurse led transition clinic - Laura Jurasek (Canada)
• Nurse led epilepsy services Australia experience - Brialie Forster (Australia)

 

2: Engagement and Support for People with Epilepsy

Chair: Sandra Dewar (USA)

• The Impact of Stigma - Action Amos (Africa)
• Nursing initiatives to reduce stigma- Monicah Murrey (Kenya)
• Approach to self management during seizure emergencies: Ireland perspective- Cora Flynn (Ireland)
• Approach to self management during seizure emergencies in resource limited countries – Tolu Olaniyan (United Kingdom)

 

3: Epilepsy as an Entry Point for Other Neurological Disorders

Chair: Peter Kabemba (Zambia)

• The lived experience. A personal journey of a parent of child with epilepsy and comorbid conditions – Deirdre-Ann Wynne Robinso (Ireland)
• Nursing opportunities in screening for comorbidities- Ludivine Rohrer (France)
• Panel and group discussion

Brainstorming sessions:

• Advantages and challenges of using SEEG for the study of the bidirectional relationships between sleep and epilepsy - Birgit Frauscher (Canada)
• Mistakes not to make in getting a therapy from the lab to the clinic- Matthew Walker (United Kingdom)
• Seizure prediction - methods, devices and future challenges – Mark Cook (Australia)

 

Career development sessions:

• Finding work-life balance and preventing burnout’ - Manjari Tripathi (India)
• Effective strategies to conduct a multicentre prospective study - Eugen Trinka (Austria)

Title: Reproductive risks associated with antiseizure medications.

Details TBC

Title: Gain- and loss-of-function variants in SCN1A-related epilepsies: phenotypic spectrum, therapeutic implications, predictive tools and functional studies guiding the choice of effective antiseizure medications.

Chair: Massimo Mantegazza (France0

• Phenotypic spectrum of loss-of-function and gain-of-function SCN1A variants – I - Andreas Brunklaus, (United Kingdom)
• Phenotypic spectrum of loss-of-function and gain-of-function SCN1A variants – II - Carla Marini (Italy)
• Algorithms and web tools for predicting functional effects of genetic variants - Dennis Lal (USA)
• Functional studies of SCN1A variants and their possible implementation into clinical workups. - Massimo Mantegazza (France)

 

Title: How to streamline up-to-date diagnostic processes in epilepsy when suspecting a rare or complex epilepsy: the ERN EpiCARE approach?

Co-chairs: Alexis Arzimanoglou (Spain) and Masa Malenica (Croatia)

Debate featuring two interactive clinical cases.

• A child with a high risk of a developmental epileptic encephalopathy – Lieven Lagae (Belgium)
• A potential candidate for surgery – Philippe Ryvlin (Switzerland)

State-of-the-art Consultants: 

Neurophysiology – Sandor Beniczky (Denmark)
Neuroimaging – Petr Marusic (Czech Republic)
Genetic screening – Rikke Steensbjerre Møller (Denmark)

 

Title: How do you start to solve epilepsy in resource limited settings?

Chair: Arjune Sen, United Kingdom

• Action Amos (Malawi)
• Mercy Atieno (Kenya)
• Sabina Asiamah (Ghana)
• Mary Bitta (Kenya)
• Emmanuel Darkwa (Ghana)
• Symon Kariuki (Kenya)
• Dorcas Muli (Kenya)
• Vivian Mushi (Tanzania)
• Daniel Mwanga (Kenya)
• Charles Newton (United Kingdom)
• Josemir Sander (United Kingdom)
• Arjune Sen (United Kingdom)
• Gangandeep Singh (India)
• Jo Wilmhurst (South Africa)

 

Title: Is precision medicine the answer to developmental and epileptic encephalopathies (DEE)

Chair: Rod Scott, USA

• Single gene approaches to precision medicine - Dennis Lal (USA)
• Limitations of single gene approaches and discussion of complex systems - Rod Scott (USA)
• Gene therapy in epilepsy
• Systems genetics approaches drug

 

Title: The high burden of Functional Dissociative Seizures: meeting the challenge

Co-Chairs: Markus Reuber (United Kingdom) and Coraline Hingray (France)

• Findings and implications of the high rate of physical morbidity and increased mortality in patients with FDS - Poul Joergen Jennum (Denmark)
• What is it like to live with FDS? Stigma, self-stigma, quality of life & education - Gregg Rawlings (United Kingdom)
• Suicide attempts and suicidal ideation in patients with FDS and epilepsy - Irene Faiman (Italy)
• Guided audience discussion - W Curt LaFrance, Jr. (USA)

 

Title: Harnessing the Power of Laws for the Intersectoral Global Action Plan - Fireside Chat

Chair: Nkandu Nchindila (Zambia)

• Gertrude Fefoame (Ghana)

 

Title: Withdrawing antiseizure medications: why, when how?

Chair: Marian Galovic (Switzerland)

• ASM withdrawal after epilepsy surgery - Lara Jehi (USA)
• ASM withdrawal in seizure-free patients - Kees Braun (Netherlands)
• Models for ASM withdrawal - Carolina Ferreira Atuesta (USA)
• Interactive case-based discussion - Samuel Terman (USA)

 

Title: Indigenous Dietary Therapies in Epilepsy: Different cultures - varied perspectives – similar outcomes

Chair: Sheffali Gulati, India

• Choosing a diet - Jo Wilmhurst (South Africa)
• Efficacy of alternatives to KD in epilepsy - Derrick Chan (Singapore)
• Non-epileptic indications of dietary therapy - Heung Dong Kim (South Korea)
• Development of a KD-pill: Removal of all restrictions? - Sheffali Gulati (India)

 

Title: Seizure or Senior Moment - The nuances of managing older people with epilepsy.

• Differentiating a seizure from other common paroxysmal events in older adults.
• The utility of different diagnostic tests and deploying them strategically in older adults.
• When to treat seizures in older adults and what clinical, etiological and practical variables to consider.
• Addressing polypharmacy: managing interactions with antiseizure medications in older adults.

 

Title: Disseminating and implementing evidence-based epilepsy self-management programs to improve patient outcomes

Chair: Erica Johnson, USA

• The Managing Epilepsy Well Network (MEWN): The Path from Science to Service
• The HOBSCOTCH Institute: Fostering Innovative Solutions for Public Health Impact in Epilepsy Self-Management - Elaine Kiriakopoulos (USA)
• MINDSET: Screening and Referring for Epilepsy Self- Management in the Clinic Setting - Ross Shegog (USA)
• SMART Program Outreach to People with Epilepsy Living in Rural Settings and Using an Integrated Dataset to Inform Dissemination Approached Depression in Clinical and Community Settings - Martha Sajatovic (USA)

 

Title: Engaging primary health care providers in epilepsy care: How and how much?

Chair: Gangandeep Singh (India)

• Josemir Sander (United Kingdom)
• Jo Wilmhurst (South Africa)
• Gangandeep Singh (India)
• Chahnez Charfi Triki (Tunisia)

 

Title: International academia-industry collaboration: implementation of EEG/ epilepsy education and research

Chair: Kensuke Kawai (Japan) and Aris Bintoro (Japan)

• Global approach of IGAP for individual chapters -Alla Guekht (Russian Federation)
• Current problems and implementation in epilepsy care in South East Asia - Fitri Octaviana (Indonesia)
• Academia-industry collaboration in Indonesia for fundamental education - Hideaki Shiraishi (Japan)
• Implementation of research beyond academia-industry collaboration - Akio Ikeda (Japan)

 

Title: When a patient with implanted electrodes should NOT be operated

Chair: Jean Gotman, Canada

• Planning an implantation to maximize the chance of success - Philippe Kahane (France)
• No operation if the seizure onset zone was missed, but how do we know it is missed? - Stanislas Lagarde (France)
• No operation if the seizure onset zone is too widespread, but what is “widespread”? - Laura Tassi (Italy)
• No operation if key interictal biomarkers are absent - Birgit Frauscher (Canada)

 

Title: MOGHE (Mild Malformation of Cortical Development with Oligodendroglial Hyperplasia in Epilepsy): A New Underdiagnosed Epileptic Brain Lesion

Co-Chairs: Till Hartlieb (Germany) and Katja Kobow (Germany)

Till Hartlieb (Germany)

Katja Kobow (Germany)

 

Title: When your world falls apart: Providing care to people with epilepsy in emergencies, crises, and disasters.

Chair: Timothy Welty, USA

• Introduction to Session and the Problem of Emergency Response - Timothy Welty (USA)
• Plans for Responding to Emergency Situations - Ali Asadi-Pooya (Iran)
• Working with Government and Nongovernment Organizations - Petra Straight (New Zealand)

 

Title: Is it time to merge ‘omics’ and epilepsy management?

Chair: Emilio Russo (Italy) and Pasquale Striano (Italy)

• Expanding Genomics toward omics holism - Hervè Blottiere, France
• Metabolomics: from complexity to usefulness
• Exploiting Microbiome for a super holobiont - Carmen de Caro (Spain)
• Clinical usefulness: one for all and all for one - Antonella Riva (Italy)

 

Title: Recent advances in normative mapping for epilepsy research and treatment

Chair: Yujiang Wang, United Kingdom

• Normative mapping in intracranial EEG - Birgit Frauscher (Canada)
• Normative mapping in across MEG and EEG - Peter Taylor (United Kingdom)
• Normative mapping in MRI - Simon Keller (United Kingdom)
• Normative mapping across measures and modalities - Jonathan Horsley (United Kingdom)

 

Pharmacy section

• Role of the Clinical Pharmacist Practitioner in a Veterans Administration Comprehensive Epilepsy Center - Barry Gidal
• Experience from the Pharmacology Team at the National Center for Epilepsy in Norway - Cecilie Johannessen Landmark (Norway)
• Pharmacist-clinician Collaboration in Epilepsy, Experiences from Israel – Sara Eyal (Israel)
• Role of Pharmacist in a Refractory Epilepsy Clinic - Sunita Dergalust

 

Neurotechnology section 

• Visual analysis: an eye and mind game - Ana Carolina Coan (Brazil)
• Advanced methods of signal processing in electrophysiology - Christian Bénar (France)
• Overview of EEG / MEG source imaging methods: from dipole modeling to advanced imaging - Christophe Grova (Canada)
• Imaging technology in epilepsy: to what extent clinicians can benefit from these approaches? - Anna Vaudano (Italy)
• Clinical example case using imaging NT - Juan Pablo Princich (Argentina)

 

Nursing Section:

• Addressing Challenges in the Epilepsy Monitoring Unit
• Spotlight on Epilepsy Nursing Education
• Innovations in Clinical Practice
• Inspiring Nurses to Empower Patients

 

Genetics of Epilepsy 2023: from patients to populations – Samuel Berkovic (Australia)

This award was created by family, colleagues and trainees of Dr Andermann to honour his legacy. This is the first, named lecture at an International Epilepsy Congress, and the aims are to enrich the congress with a full lecture by a prominent epileptologist, honouring the memory of Fred Andermann, and also to honour the lecturer.

In memoriam Frederick Andermann

 

• The ILAE Publication Landscape – Jean Gotman (Canada)
• ILAE Wikipedia Epilepsy Workshop: A Prestigious project for the League – Samuel Wiebe (Canada)
• Before and After Edits – Nandan Yardi
• The Wikipedia Editing Process: Editing Samples and Collaborations – Amin Azzam
• The Wikipedia Editing Process: My Experience as a Contributor – Jonah Fox
• The AES Wikipedia task force – Jaideep Kapur
• Where We stand Today and The Way Ahead – Diptanshu Das

Award Symposium: Epilepsia Open Prize 2023 - Basic Science

Focal impaired awareness seizures in a rodent model: a functional anatomy – Nadia Adotevi (USA)

 

Award Symposium: Epilepsia Open Prize 2023 – Clinical

Risk factors that predict delayed seizure detection on continuous electroencephalogram (cEEG) in a large sample size of critically ill patients – Ifrah Zawar (USA)

 

Award Symposium: Epilepsia Prize 2023- Clinical

Clinical and EEG factors associated with antiseizure medication resistance in idiopathic generalized epilepsy – Brad Kamitaki (USA)

 

Award Symposium: Epilepsia Prize 2023- Basic Science

Hippocampal position and orientation as prognostic biomarkers for posttraumatic epileptogenesis: An experimental study in a rat lateral fluid percussion model – Riccardo De Feo (Finland)

 

Award Symposium: Epileptic Disorders Prize 2023

The operational definition of epileptiform discharges significantly improves diagnostic accuracy and inter-rater agreement of trainees in EEG reading – Mustafa Aykut Kural (Denmark)

The 35th International Epilepsy Congress, Dublin, Ireland, 02/09/2023-06/09/2023 has been accredited by the European Accreditation Council for Continuing Medical Education (EACCME®) with 35 European CME credits (ECMEC®s). Each medical specialist should claim only those hours of credit that he/she actually spent in the educational activity.

Through an agreement between the Union Européenne des Médecins Spécialistes and the American Medical Association, physicians may convert EACCME® credits to an equivalent number of AMA PRA Category 1 CreditsTM. Information on the process to convert EACCME® credit to AMA credit can be found at www.ama-assn.org/education/earn-credit-participation-international-activities.

Live educational activities, occurring outside of Canada, recognised by the UEMS-EACCME® for ECMEC®s are deemed to be Accredited Group Learning Activities (Section 1) as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.

Each participant can only receive the number of credits he/she is entitled to according to his/her actual participation at the event once he/she has completed the feedback form.

If you have any questions, please contact the Congress Secretariat at iec@epilepsycongress.org

 

Instructions for converting EACCME® credits to AMA PRA Category 1 Credit™

WONOEP highlights session: The extracellular space in epilepsy: pathomechanisms, biomarkers and treatment targets
Chairs: David Henshall (Ireland) and Aristea Galanopoulou (USA)

• The role of the extracellular matrix in epilepsy – Chris Dulla (USA)
• The immunopathogenesis of epilepsy – TBA
• Ion and channel function beyond the synapse – Marco De Curtis (Italy)
• Emerging mechanisms in epilepsy beyond the synapse – TBA
• Biomarkers and treatment strategies beyond the synapse – Ozlem Akman (Turkey)