Useful COVID-19 References for Clinicians

Seizures in COVID-19

Genetic epilepsies and COVID‐19 pandemic: Lessons from the caregiver perspective
Ángel Aledo‐Serrano et al. Epilepsia. 18 May 2020

Seizures associated with coronavirus infections
Ali A. Asadi-Pooya. Seizure 79 (2020) 49-52

New-onset acute symptomatic seizure and risk factors in Corona Virus Disease 2019: A Retrospective Multicenter Study.
Lu et al Epilepsia. 2020 Apr 18. doi: 10.1111/epi.16524. [Epub ahead of print]

Seasonal distribution of febrile seizure and the relationship with respiratory and enteric viruses in Korean children based on nationwide registry data
Han DH, Kim SY, Lee NM, Yi DY, Yun SW, Lim IS, Chae SA. Seizure. 2019 Dec;73:9-13. doi: 10.1016/j.seizure.2019.10.008. Epub 2019 Oct 18

The impact of SARs on epilepsy; the experience of drug withdrawal in epileptic patients
Lai et al Seizure 2005;14:557-561

Neurological complications

Neuropathogenesis and Neurologic Manifestations of the Coronaviruses in the Age of Coronavirus Disease 2019: A Review. Adeel S. Zubair, MD1; Lindsay S. McAlpine, MD1; Tova Gardin, MD, MPP1; et al. JAMA Neurol. Published online May 29, 2020. doi:10.1001/jamaneurol.2020.2065

Neurologic Features in Severe SARS-CoV-2 Infection. Helms J, Kremer S, Merdji H, et al. N Engl J Med, April 15 2020.

Central nervous system manifestations of COVID-19: A systematic review.
Asadi-Pooya AA, Simani L. J Neurol Sci. 2020 Apr 11;413:116832

Neurological Manifestations of Hospitalized Patients with COVID-19 in Wuhan, China: a retrospective case series study [Online]. Mao L, Wang M, Chen S, et al. JAMA Neurology April 10. doi:10.1001/jamaneurol.2020.1127

Neurological manifestations in COVID19 caused by SARS-CoV-2
Baig AM CNS Neurosci Ther 2020;26:499-501

The Spectrum of Neurologic Disease in the Severe Acute Respiratory Syndrome Coronavirus 2 Pandemic Infection: Neurologists Move to the Frontlines.
Pleasure SJ, Green AJ, Josephson SA. JAMA Neurol. 2020 Apr 10. doi: 10.1001/jamaneurol.2020.1065

Acute Cerebrovascular Disease Following COVID-19: A Single Center, Retrospective, Observational Study.
Li Y, Wang M, Zhou Y, et al. 2020. Accessed on April 4, 2020. This article is a preprint and has not been peer-reviewed.

A first case of meningitis/encephalitis associated with SARS-Coronavirus-2.
Moriguchi T, Harii N, Goto J, Harada D, Sugawara H, Takamino J, Ueno M, Sakata H, Kondo K, Myose N, Nakao A, Takeda M, Haro H, Inoue O, Suzuki-Inoue K, Kubokawa K, Ogihara S, Sasaki T, Kinouchi H, Kojin H, Ito M, Onishi H, Shimizu T, Sasaki Y, Enomoto N, Ishihara H, Furuya S, Yamamoto T, Shimada S.
Int J Infect Dis. 2020 Apr 3;94:55-58

Headaches Associated With Personal Protective Equipment - A Cross-Sectional Study Among Frontline Healthcare Workers During COVID-19.
Ong JJY, Bharatendu C, Goh Y, Tang JZY, Sooi KWX, Tan YL, Tan BYQ, Teoh HL, Ong ST, Allen DM, Sharma VK. Headache. 2020 Mar 30. doi: 10.1111

Neurologic complications of coronavirus infections.
Nath A. Neurology. 2020 Mar 30.

Neurologic alterations due to respiratory virus infections
Bohmwald et al Front Cell Neurosci 2018;12:386


What should we ask patients with epilepsy on telemedicine during the COVID-19 crisis? A checklist for clinicians. Kuroda N. Epilepsy Behav. 2020 May 25;111:107184. doi: 10.1016/j.yebeh.2020.107184. Online ahead of print. Download as pdf

Telemedicine for Epilepsy Care in the COVID-19 Era: Key points to address + links to resources

EEG in COVID-19 patients

EEG findings in acutely ill patients investigated for SARS‐CoV2/COVID‐19: a small case series preliminary report. Aristea S. Galanopoulou, Victor Ferastraoaru, Daniel J. Correa, Koshi Cherian, Susan Duberstein, Jonathan Gursky, Rajani Hanumanthu, Christine Hung, Isaac Molinero, Olga Khodakivska, Alan D. Legatt, Puja Patel, Jillian Rosengard, Elayna Rubens, William Sugrue, Elissa Yozawitz, Mark F. Mehler, Karen Ballaban‐Gil, Sheryl R. Haut, Solomon L. Moshé, Alexis Boro. Epilepsia Open. 06 May 2020. doi: 10.1002/eip4.12399

Mental health

COVID‐19 outbreak: The impact of stress on seizures in patients with epilepsy Shanshan Huang, Chunmei Wu, Yuchao Jia, Guo Li, Zhou Zhu, Kai Lu, Yuyan Yang, Furong Wang, Suiqiang Zhu. Epilepsia.2020;00:1-10. DOI: 10.1111/epi.16635

Multidisciplinary research priorities for the COVID-19 pandemic: a call for action for mental health science.
Emily A Holmes, Rory C O’Connor, V Hugh Perry, Irene Tracey, Simon Wessely, Louise Arseneault, Clive Ballard, Helen Christensen, Roxane Cohen Silver, Ian Everall, Tamsin Ford, Ann John, Thomas Kabir, Kate King, Ira Madan, Susan Michie, Andrew K Przybylski, Roz Shafran, Angela Sweeney, Carol M Worthman, Lucy Yardley, Katherine Cowan, Claire Cope, Matthew Hotopf, Ed Bullmore.
Lancet Psych 2020 epub on line


Maternal and neonatal outcomes of pregnant women with COVID-19 pneumonia: a case-control study.
Li N, Han L, Peng M, Lv Y, Ouyang Y, Liu K, Yue L, Li Q, Sun G, Chen L, Yang L. Clin Infect Dis. 2020 Mar 30.

Why are pregnant women susceptible to COVID-19? An immunological viewpoint.
Liu H, Wang LL, Zhao SJ, Kwak-Kim J, Mor G, Liao AH. J Reprod Immunol. 2020 Mar 19;139:103122.


Animal Models for Emerging Coronavirus: Progress and New Insights. Yuan L, Tang Q, Cheng T, et al. Emerg Microbes Infect, 2020, 1-26

The neuroinvasive potential of SARS-CoV2 may play a role in the respiratory failure of COVID-19 patients. Li YC, Bai WZ & Hashikawa T. J Med Virol, 2020.

The pathogenicity of SARS-CoV-2 in hACE2 transgenic mice. Bao L, Deng W, Huang B, et al. Nature, 2020.

Profile of a killer: the complex biology powering the coronavirus pandemic. Cyranoski D. Nature, 2020; 581, 22-26.

A SARS-CoV-2 protein interaction map reveals targets for drug repurposing. Gordon DE, Jang GM, Bouhaddou M, et al. Nature, 2020.

On Facing the SARS-CoV-2 (COVID-19) with Combination of Nanomaterials and Medicine: Possible Strategies and First Challenges. Sivasankarapillai VS, Pillai AM, Rahdar A, et al. Nanomaterials (Basel), 2020; 10.