Ketogenic Diet Articles

The list of articles below link to free access articles about the Ketogenic Diet, organized by date.

The ILAE Task Force on Dietary Therapy would like to acknowledge the generous support of Epilepsia®, Epilepsy and Behavior, and Journal of Child Neurology for their donations of these key articles. This list is by no means all-inclusive, but rather represents important articles as chosen by the Task Force.

The ketogenic diet for super-refractory status epilepticus
Epigraph, Winter 2021

La dieta cetogénica para el estado epiléptico superrefractario
Epigraph, Winter 2021

The ketogenic diet as epilepsy treatment
Epigraph, Fall 2020

Ketogenic diets in low-resource settings: A snapshot from Zambia
Epigraph, Fall 202

Optimal clinical management of children receiving ketogenic parenteral nutrition: a clinical practice guide
Eles van der Louw et al. Developmental Medicine & Child Neurology. May 2019. DOI: 10.1111/dmcn.14306 PDF

Optimal clinical management of children receiving dietary therapies for epilepsy: Updated recommendations of the International Ketogenic Diet Study Group
Eric H. Kossoff et al. Epilepsia Open, 1–18, 2018. doi: 10.1002/epi4.12225

Optimal clinical management of children receiving the ketogenic diet: recommendations of the International Ketogenic Diet Study Group.
Kossoff EH, Zupec-Kania BA, Amark PE, Ballaban-Gil KR, Christina Bergqvist AG, Blackford R, et al.
Epilepsia. 2009; 50(2): 304-17.

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Optimal clinical management of children receiving the ketogenic diet - Vietnamese

Efficacy and tolerability of the ketogenic diet versus high‐dose adrenocorticotropic hormone for infantile spasms: A single‐center parallel‐cohort randomized controlled trial
Anastasia Dressler et al. Epilepsia 2019:60: 441-451.

The Gut Microbiota Mediates the Anti-Seizure Effects of the Ketogenic Diet
Christine A. Olson et al. Cell. Published:May 24, 2018. 173, 1728-1741.

Genome-wide association study: Exploring the genetic basis for responsiveness to ketogenic dietary therapies for drug‐resistant epilepsy
Natasha E. Schoeler et al.Epilepsia 2018:59: 1557-1566.

Effect of modified Atkins diet in adults with drug-resistant focal epilepsy: A randomized clinical trial
Magnhild Kverneland et al. Epilepsia 2018:1-10. doi:10.11111/epi14457.

Ketogenic diet for treatment of intractable epilepsy in adults: A meta‐analysis of observational studies
Liu et al. Epilepsia Open.15 January 2018.

Efficacy of the classic ketogenic and the modified Atkins diets in refractory childhood epilepsy
Jeong A. Kim et al. Epilepsia 57(1): 51-58, 2016. doi: 10.1111/epi.13256.

Establishing an Adult Epilepsy Diet Center: Experience, efficacy and challenges
Mackenzie C. Cervenka et al. Epilepsy & Behavior 58 (2016) 61-68. doi: 10.1016/j.yebeh.2016.02.038.

>Ketogenic diet exhibits anti-inflammatory properties
Nina Dupuis et al. Epilepsia, 56(7):e95-e98, 2015. doi: 10.1111/epi.13038.

First Application of Ketogenic Diet on a Child With Intractable Epilepsy in Ghana
Dezhi Cao, Eben Badoe, Yanwei Zhu, Xia Zhao, Yan Hu, Jianxiang Liao
Child Neurology Open, July - September 2015 vol. 2 no. 3. Published September 21, 2015, doi: 10.1177/2329048X15604593
The authors successfully used the ketogenic diet with a 10 month old girl with epilepsy with unknown etiology whose seizures couldn’t be controlled with antiepileptic drugs. Her seizures were completely controlled after 2 weeks' therapy. Her mental condition was improved after that. This is the first case with epilepsy treated by ketogenic diet in Ghana as well as in West Africa according to current information available. The authors' experience from this case will be an aid to further developing the ketogenic diet in Africa.


What are the minimum requirements for ketogenic diet services in resource-limited regions? Recommendations from the ILAE Task Force for Dietary Therapy
Eric H. Kossoff, Nabil Al-Macki, Mackenzie C. Cervenka, Heung D. Kim, Jianxiang Liao, Katherine Megaw, Janak K. Nathan, Ximena Raimann, Rocio Rivera, Adelheid Wiemer-Kruel, Emma Williams, and Beth A. Zupec-Kania
Epilepsia DOI: 10.1111/epi.13039. First published online: 29 May 2015

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Use of Dietary Therapy for Status Epilepticus
Kossoff EH, Nabbout R
J Child Neurol, 2013; 28(8): 1049-51., first published on May 1, 2013

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Use of the modified Atkins diet for treatment of refractory childhood epilepsy: a randomized controlled trial
Sharma S, Sankhyan N, Gulati S, Agarwala A. Epilepsia. 2013; 54(3): 481-6.

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A decade of the modified Atkins diet (2003-2013): Results, insights, and future directions
Kossoff EH, Cervenka MC, Henry BJ, Haney CA, Turner Z.
Epilepsy Behav. 2013; 29(3): 437-42


Long-Term Follow-Up of Children Treated With the Modified Atkins Diet
Chen W, Kossoff EH
J Child Neurol, June 2012; 27(6): 754-758., first published on April 24, 2012

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How do parents find out about the ketogenic diet?
Kossoff EH, Doerrer SS, Turner Z.
Epilepsy Behav. 2012; 24(4): 445-8.


The ketogenic and related diets in adolescents and adults-A review
Payne NE, Cross JH, Sander JW, Sisodiya SM.
Epilepsia. 2011; 52(11): 1941-8.

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Dietary treatments for epilepsy: Management guidelines for the general practitioner
Lee PR, Kossoff EH.
Epilepsy Behav. 2011; 21(2): 115-21.


Long-term outcomes of children treated with the ketogenic diet in the past
Patel A, Pyzik PL, Turner Z, Rubenstein JE, Kossoff EH.
Epilepsia. 2010. 51(7): 1277-82.

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Infantile spasms treated with the ketogenic diet: prospective single-center experience in 104 consecutive infants
Hong AM, Turner Z, Hamdy RF, Kossoff EH.
Epilepsia. 51(8): 1403-7.

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Ketogenic Diets: An update for child neurologists
Kossoff EH, Zupec-Kania BA, Rho JM.
J Child Neurol 2009;24(8):979-988.


A blinded, crossover study of the efficacy of the ketogenic diet
Freeman JM, Vining EP, Kossoff EH, Pyzik PL, Ye X, Goodman SN.
Epilepsia. 2009; 50
(2): 322-5.

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Management and risk factors for dyslipidemia with the ketogenic diet
Nizamuddin J, Turner Z, Rubenstein JE, Pyzik PL, Kossoff EH
J Child Neurol. 2008; 23(7): 758-61


A case-control evaluation of the ketogenic diet versus ACTH for new-onset infantile spasms
Kossoff EH, Hedderick EF, Turner Z, Freeman JM.
Epilepsia. 2008; 49(9): 1504-9.

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The modified Atkins diet: a potential treatment for developing countries
Kossoff EH, Dorward JL, Molinero MR, Holden KR.
Epilepsia. 2008; 49(9): 1646-7.

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A modified Atkins diet is effective for the treatment of intractable pediatric epilepsy
Kossoff EH, McGrogan JR, Bluml RM, Pillas DJ, Rubenstein JE, Vining EP.
Epilepsia. 2006; 47(2): 421-4.

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Worldwide use of the ketogenic diet.
Kossoff EH, McGrogan JR.
Epilepsia. 2005; 46(2): 280-9.

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Current treatment of myoclonic astatic epilepsy: clinical experience at the Children's Hospital of Philadelphia
Kilaru S, Bergqvist AG.
Epilepsia. 2007; 48(9): 1703-7.

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Efficacy and tolerability of the ketogenic diet according to lipid:nonlipid ratios--comparison of 3:1 with 4:1 diet
Seo JH, Lee YM, Lee JS, Kang HC, Kim HD.
Epilepsia. 2007; 48(4): 801-5.

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Fasting versus gradual initiation of the ketogenic diet: a prospective, randomized clinical trial of efficacy
Bergqvist AG, Schall JI, Gallagher PR, Cnaan A, Stallings VA.
Epilepsia. 2005; 46(11): 1810-9.

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Complications of the ketogenic diet
Ballaban-Gil K, Callahan C, O'Dell C, Pappo M, Moshe S, Shinnar S.
Epilepsia. 1998; 39(7): 744-8.

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