ILAE-North America
The current ILAE-North America region was constituted in 2006, comprising English speaking North American Chapters of Canada, the United States of America, and the English speaking Caribbean (represented by Jamaica). The Mexican chapter, although geographically in North America, is a member of the Latin American Regional Commission.
Our goals and aims are aligned with the ILAE’s emphasis on current and emerging knowledge on epilepsy prevention, diagnosis, treatment, research, and optimal comprehensive epilepsy care.
Global Health in Epilepsy Project Database
The Global Health Task Force has just launched an initiative to identify and connect international projects aimed at reducing the global epilepsy treatment gap, and it is now accepting ongoing, completed, and upcoming projects.
The goals are to increase collaboration, amplify impact, reduce redundancy, engage possible funders, and identify service opportunities.
Latest News
About ILAE
Transition in Epilepsy – A survey for patients and healthcare practitioners
Transition from pediatric to Adult Healthcare System proves difficult for many youths with epilepsy and their families. There are significant difficulties in establishing and maintaining transition programs in epilepsy. The purpose of the study is to understand the patient/caregiver and healthcare professional’s perspective of transition in epilepsy and the barriers experienced.
7 September, 2021
Basic Science
Activation of the basal ganglia and indirect pathway neurons during frontal lobe seizures
These studies, for the first time, show activation of neurons in the striatum, globus pallidus, subthalamic nucleus, and substantia nigra during frontal lobe motor seizures on the cellular level, revealing a complex neuronal activation circuit subject to modulation by the basal ganglia.
23 August, 2021
Clinical Research
Towards realizing the vision of precision medicine: AI based prediction of clinical drug response
We used the anti-epileptic drug brivaracetam as a case study and combine a hybrid data/knowledge-driven feature extraction with machine learning to systematically integrate clinical and genetic data from a clinical discovery dataset. We constructed a model that successfully predicts clinical drug response and show that even with limited sample size, integrating high-dimensional genetics data with clinical data can inform drug response prediction.
16 August, 2021
Clinical Research
Post-ictal psychosis in epilepsy: A clinico-genetic study
Post-ictal psychosis occurs under particular circumstances in people with epilepsy with a heightened genetic predisposition to schizophrenia, illustrating how disease biology (seizures) and trait susceptibility (schizophrenia) may interact to produce particular outcomes (post-ictal psychosis) in a common disease.
2 August, 2021
Clinical Research
Cardiac Autonomic Dysfunction and Risk of Sudden Unexpected Death in Epilepsy
Most of patients with subsequent SUDEP have an abnormal cardiac autonomic response to sympathetic stimulation through hyperventilation. An index reflecting the change in HR on hyperventilation might be predictive of the risk of SUDEP and could be used to select patients at risk of SUDEP for inclusion in trials assessing protective measures.
28 July, 2021
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