Epilepsia Open® Top Viewed Articles
Epilepsia Open’s Most-Read Articles by Year
Explore the most downloaded and viewed Epilepsia Open articles from each publication year. These papers highlight impactful research, clinical advances, and key developments in epilepsy that have captured the attention of our global readership.
2025
Genetic epilepsies with myoclonic seizures: Mechanisms and syndromes
Epilepsy syndromes classification
The use of steroids in adult epilepsy: A systematic review
Interim analysis of the long-term efficacy and safety of azetukalner in an ongoing open label extension study following a phase 2b clinical trial (XTOLE) in adults with focal epilepsy
Real world effectiveness and tolerability of cenobamate in drugresistant epilepsy: A retrospective analysis of the patients included into the Early Access Programs (EAP) in Germany, France, and United Kingdom
Status epilepticus: Updates on mechanisms and treatments
Communicating a diagnosis of Dravet syndrome to parents/caregivers: An international Delphi consensus
Precision therapies for genetic epilepsies in 2025: Promises and pitfalls
The impact of ketogenic diet on the frequency of psychogenic nonepileptic seizures (PNES): A feasibility randomized pilot study
The upside of epilepsy: Theories of an evolutionary paradox
2024
Myoclonus: Differential diagnosis and current management
Refining management strategies for Lennox-Gastaut syndrome: Updated algorithms and practical approaches
Consensus panel recommendations for the optimization of EPIDIOLEX treatment for seizures associated with Lennox Gastaut syndrome, Dravet syndrome, and tuberous sclerosis complex
Comparative efficacy and safety of stiripentol, cannabidiol and fenfluramine as first line addon therapies for seizures in Dravet syndrome: A network meta-analysis
Epilepsy, EEG and chromosomal rearrangements
Pediatric neuromodulation for drug resistant epilepsy: Survey of current practices, techniques, and outcomes across US epilepsy centers
Defining neonatal status epilepticus: A scoping review from the ILAE neonatal task force
Potassium channel related epilepsy: Pathogenesis and clinical features
Practical considerations for the use of fenfluramine to manage patients with Dravet syndrome or LennoxGastaut syndrome in clinical practice
2023
EEG datasets for seizure detection and prediction- A review
Dravet syndrome: A systematic literature review of the illness burden
Cenobamate in refractory epilepsy: Overview of treatment options and practical considerations
Real-world data on cannabidiol treatment of various epilepsy subtypes: A retrospective, multicenter study
Real-world safety and effectiveness of cenobamate in patients with focal onset seizures: Outcomes from an Expanded Access Program
Sudden unexpected death in epilepsy: A critical view of the literature
Role of the glymphatic system and perivascular spaces as a potential biomarker for poststroke epilepsy
Epileptic Status in a PEDiatric cohort (ESPED) requiring intensive care treatment: A multicenter, national, two-year prospective surveillance study
Landscape of genetic infantile epileptic spasms syndrome-A multicenter cohort of 124 children from India
Efficacy of vigabatrin in the treatment of infantile epileptic spasms syndrome: A systematic review and metaanalysis