Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (IGAP)

Joint ILAE and IBE cascade target regarding the draft Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders: 
-90% of all people with epilepsy aware of their diagnosis as a treatable brain disorder
-80% of people diagnosed with epilepsy with access to appropriate, affordable, safe antiseizure medicines
-70% of people with epilepsy on treatment achieve adequate seizure control

In November 2020, the Seventy-third World Health Assembly (WHA) adopted resolution WHA 73.10 on Global actions on epilepsy and other neurological disorders to develop an Intersectoral global action plan on epilepsy and other neurological disorders (IGAP) in consultation with Member States. The action plan will address the challenges and gaps in providing care and services for people with epilepsy and other neurological disorders that exist worldwide and ensure a comprehensive, coordinated response across sectors.

ILAE and IBE jointly advocated for a 90-80-70 cascade target for epilepsy to be included in the IGAP to inspire a decade of action and achieve meaningful improvements in care and treatment for all of the 50 million plus people who live with epilepsy globally.

The WHO Secretariat prepared a revised draft of the Intersectoral global action plan on epilepsy and other neurological disorders (EB150/7 Annex 7) that was submitted for review at the 150th session of the Executive Board in January 2022. The ILAE position statement given at the session commended the inclusion of Target 5.1 addressing epilepsy services and Target 5.2 tackling discrimination, remarking that epilepsy is highly treatable – and both stigma and exclusion are preventable. ILAE noted that all ten target areas in the draft IGAP are relevant to epilepsy and recommended that all use the phrase ‘epilepsy and other neurological disorders’ to align with Resolution WHA 73.10.

On 27 January 2022, the draft IGAP was approved at the 150th session of the WHO Executive Board. ILAE was grateful for the attention to the needs of people with epilepsy on part of the WHO, as well as to all Executive Board members who spoke in favour of the draft IGAP.

In May 2022, during the 75th World Health Assembly in Geneva, Switzerland, four international organizations and 116 Member States spoke in support of the IGAP. On 27 May 2022, WHO Member States unanimously approved the plan

To meet the global targets, IGAP includes proposed actions for WHO Member States, the WHO Secretariat, and national and international partners in several areas:

Access to services for epilepsy – Approximately 70% of people with epilepsy can be seizure free with treatment. However, treatment gaps exist in every country in the world. The current treatment gap estimate is 75% in lower-income countries and is substantially higher in rural areas.

Engagement and support for people with epilepsy – People with epilepsy and their families are stigmatized and discriminated against as a result of the misconceptions and negative attitudes that surround epilepsy. This leads to human rights violations and social exclusion. In some settings, children with epilepsy may not be allowed to attend school; adults may not be able to find suitable employment or to marry.

Epilepsy as an entry point for other neurological disorders – Epilepsy can be secondary to other neurological conditions, such as stroke or traumatic brain injury. It also can occur along with other conditions; for example, 19% of people with epilepsy also have migraine, and about 26% of adults with epilepsy also have intellectual disability.

With support, the IGAP will help to strengthen the prevention, detection, care, treatment, and equal opportunities for people with epilepsy and other neurological disorders worldwide.

Learn more about IGAP | Watch the IGAP: What's Next? webinar

A History of Initiatives to Reduce the Global Burden of Epilepsy

Click the image below to view the full-size infographic with interactive links.

WHO History of initiatives to reduce the global burden of epilepsy infographic
A History of Initiatives to Reduce the Global Burden of Epilepsy PDF

First draft of the IGAP

Click the image below to read the draft Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders, June 2021.

First draft of the Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (IGAP), June 2021. Click to read PDF.
First draft of the IGAP PDF

ILAE/IBE Virtual Roundtable

Click the image below to read the report on the virtual roundtable held by ILAE and IBE, 16 July 2021.

Report on the virtual roundtable discussion held by ILAE and IBE,16 July 2021. Click to read PDF.
Report on the virtual roundtable discussion PDF

Epilepsy 90-80-70: A SMART Target

Click the image below to read how the proposed cascade target is specific, measurable, achievable, relevant, and time bound.

Epilepsy 90-80-70: A SMART Target. Click to read PDF.
Epilepsy 90-80-70: A SMART Target PDF

Joint ILAE/IBE IGAP recommendations

Click the image below to read the ILAE and IBE letter to WHO, 28 July 2021.

Joint ILAE/IBE letter to WHO with IGAP recommendations click to read
Joint ILAE/IBE IGAP recommendations PDF

ILAE, ICNA & WFN IGAP recommendations

Click the image below to read the letter to the WHO from ILAE, the International Child Neurology Association and the World Federation of Neurology, 12 August 2021.

Letter to the World Health Organization from ILAE, the International Child Neurology Association and the World Federation of Neurology with three key recommendations to reflect in the Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (IGAP), 12 August 2021. Click to read PDF.
ILAE, ICNA & WFN IGAP recommendations PDF

ILAE review of IGAP comments

Click the image below to read the letter written by J Helen Cross on behalf of ILAE to the WHO, 13 October 2021.

Letter to the World Health Organization from Prof J Helen Cross on behalf of ILAE reacting to the document circulated with comments on the draft Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (IGAP), 13 October 2021. Click to read PDF.
ILAE review of IGAP comments PDF

Revised draft of the IGAP

Click the image below to read the revised draft Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (EB150/7 Annex 7), 11 January 2022.

Revised draft of the Intersectoral Global Action Plan on Epilepsy and Other Neurological Disorders (IGAP) 2022-2031 (EB150/7 Annex 7) , 11 January 2022. Click to read PDF.
Revised draft of the IGAP PDF

ILAE position statement on revised draft IGAP

Click the image below to read the position statement given by J Helen Cross on behalf of ILAE at the 150th session of the WHO Executive Board, 27 January 2022.

ILAE position statement re: EB150/1, agenda item 7: (g) Draft intersectoral global action plan on epilepsy and other neurological disorders at the 150th session of the World Health Organization Executive Board, 27 January 2022. Click to read the PDF.
ILAE statement on revised IGAP PDF

IGAP global report

Click the image below to read the Intersectoral global action plan on epilepsy and other neurological disorders (2022-2031), 20 July 2023.

World Health Organization
Intersectoral global action plan on epilepsy and other neurological disorders
2022-2031
IGAP global report PDF

Global campaign origins

Click the image below to read The origins and early development of the ILAE/IBE/WHO global campaign against epilepsy: Out of the shadows, Epilepsia Open (2023).

Reynolds, EH. The origins and early development of the ILAE/IBE/WHO global campaign against epilepsy: Out of the shadows. Epilepsia Open. 2023; 00: 1–7. https://doi.org/10.1002/epi4.12850
Global campaign origins

IGAP implementation toolkit

Click the image below to read the Intersectoral global action plan on epilepsy and other neurological disorders 2022–2031: implementation toolkit, 8 July 2024.

Intersectoral global action plan on epilepsy and other neurological disorders 2022-2031:
implementation toolkit
World Health Organization
IGAP implementation toolkit PDF

For more information on IGAP, visit the WHO website.

Epilepsy 90-80-70

90% of all people with epilepsy aware of their diagnosis as a treatable brain disorder

  • Increased public and professional awareness about epilepsy
  • Improved diagnosis through training and enhanced specialist networks
  • Harmful myths replaced with an understanding that epilepsy is a treatable brain disorder

80% of people diagnosed with epilepsy with access to appropriate, affordable, safe antiseizure medicines

  • Strengthened, sustainable essential medicine supply chains
  • Proper financing and pricing to ensure that anti-seizure medicines are affordable
  • Reclassification of certain anti-seizure medicines to allow production and importation

70% of people with epilepsy on treatment achieve adequate seizure control

  • Investment in primary and community care and support
  • People with epilepsy informed, engaged and empowered
  • Continued research to improve treatment options

Is it feasible? Could we achieve these targets?

Yes, it is feasible. There is a strong evidence base to support all of the areas listed above. It is possible to detect, diagnose and treat epilepsy through a primary health care approach.

Yes, we could achieve these targets by 2031. With strong government commitment, investment, greater inclusion and understanding, all three targets could be achieved within a decade.