Chapter Name: Hungarian Epilepsy League
Report By: Andras Fogarasi (President)

Publications:

1: Halász P, Kelemen A, Rosdy B, Rásonyi G, Clemens B, Szűcs A. Perisylvian
epileptic network revisited. Seizure. 2019 Feb;65:31-41. doi:
10.1016/j.seizure.2018.12.003. Epub 2018 Dec 21. PMID: 30605881.

2: Clemens B, Dömötör J, Emri M, Puskás S, Fekete I. Inter-ictal network of
focal epilepsy and effects of clinical factors on network activity. Clin
Neurophysiol. 2019 Feb;130(2):251-258. doi: 10.1016/j.clinph.2018.11.022. Epub
2018 Dec 16. PMID: 30583272.

3: Liu A, Vöröslakos M, Kronberg G, Henin S, Krause MR, Huang Y, Opitz A, Mehta
A, Pack CC, Krekelberg B, Berényi A, Parra LC, Melloni L, Devinsky O, Buzsáki G.
Immediate neurophysiological effects of transcranial electrical stimulation. Nat
Commun. 2018 Nov 30;9(1):5092. doi: 10.1038/s41467-018-07233-7. PMID: 30504921;
PMCID: PMC6269428.

4: Tényi D, Bóné B, Horváth R, Komoly S, Illés Z, Beier CP, Kelemen A, Kovács N,
Darnai G, Janszky J. Ictal piloerection is associated with high-grade glioma and
autoimmune encephalitis-Results from a systematic review. Seizure. 2019
Jan;64:1-5. doi: 10.1016/j.seizure.2018.11.009. Epub 2018 Nov 22. PMID:
30497014.

5: Rosen BQ, Krishnan GP, Sanda P, Komarov M, Sejnowski T, Rulkov N, Ulbert I,
Eross L, Madsen J, Devinsky O, Doyle W, Fabo D, Cash S, Bazhenov M, Halgren E.
Simulating human sleep spindle MEG and EEG from ion channel and circuit level
dynamics. J Neurosci Methods. 2019 Mar 15;316:46-57. doi:
10.1016/j.jneumeth.2018.10.002. Epub 2018 Oct 6. PMID: 30300700; PMCID:
PMC6380919.

6: Barta H, Jermendy A, Kolossvary M, Kozak LR, Lakatos A, Meder U, Szabo M,
Rudas G. Prognostic value of early, conventional proton magnetic resonance
spectroscopy in cooled asphyxiated infants. BMC Pediatr. 2018 Sep 15;18(1):302.
doi: 10.1186/s12887-018-1269-6. PMID: 30219051; PMCID: PMC6139158.

7: Kovacs-Nagy R, Morin G, Nouri MA, Brandau O, Saadi NW, Nouri MA, van den
Broek F, Prokisch H, Mayr JA, Wortmann SB. HTRA2 Defect: A Recognizable Inborn
Error of Metabolism with 3-Methylglutaconic Aciduria as Discriminating Feature
Characterized by Neonatal Movement Disorder and Epilepsy-Report of 11 Patients.
Neuropediatrics. 2018 Dec;49(6):373-378. doi: 10.1055/s-0038-1667345. Epub 2018
Aug 16. PMID: 30114719.

8: Richards KL, Milligan CJ, Richardson RJ, Jancovski N, Grunnet M, Jacobson LH,
Undheim EAB, Mobli M, Chow CY, Herzig V, Csoti A, Panyi G, Reid CA, King GF,
Petrou S. Selective Na<sub>V</sub>1.1 activation rescues Dravet syndrome mice
from seizures and premature death. Proc Natl Acad Sci U S A. 2018 Aug
21;115(34):E8077-E8085. doi: 10.1073/pnas.1804764115. Epub 2018 Aug 3. PMID:
30076230; PMCID: PMC6112713.

9: Tóth Z, Lukács G, Cselik Z, Bajzik G, Egyed M, Vajda Z, Borbély K, Hadjiev
J, Gyarmati T, Emri M, Kovács Á, Repa I. Hungarian clinical
application opportunities of PET/MR imaging and first experiences. Orv Hetil.
2018 Aug;159(34):1375-1384. Hungarian. doi: 10.1556/650.2018.31141. PMID:
30122057.

10: Papp-Hertelendi R, Tényi T, Hadzsiev K, Hau L, Benyus Z, Csábi G. First
report on the association of SCN1A mutation, childhood schizophrenia and autism
spectrum disorder without epilepsy. Psychiatry Res. 2018 Dec;270:1175-1176. doi:
10.1016/j.psychres.2018.07.028. Epub 2018 Jul 19. PMID: 30060894.

11: Nagy G, Stokes SS, Erőss LG, Bhattacharyya D, Yianni J, Rowe JG, Kemeny AA,
Radatz MWR. Contemporary radiosurgery of cerebral cavernous malformations: Part
2. Treatment outcome for hemispheric lesions. J Neurosurg. 2018 Jul 1:1-9. doi:
10.3171/2018.2.JNS171267. Epub ahead of print. PMID: 30052157.

12: Ujma PP, Halász P, Simor P, Fabó D, Ferri R. Increased cortical involvement
and synchronization during CAP A1 slow waves. Brain Struct Funct. 2018
Nov;223(8):3531-3542. doi: 10.1007/s00429-018-1703-4. Epub 2018 Jun 27. PMID:
29951916.

13: Fiáth R, Hofer KT, Csikós V, Horváth D, Nánási T, Tóth K, Pothof F, Böhler
C, Asplund M, Ruther P, Ulbert I. Long-term recording performance and
biocompatibility of chronically implanted cylindrically-shaped, polymer-based
neural interfaces. Biomed Tech (Berl). 2018 Jun 27;63(3):301-315. doi:
10.1515/bmt-2017-0154. PMID: 29478038.

14: David F, Çarçak N, Furdan S, Onat F, Gould T, Mészáros Á, Di Giovanni G,
Hernández VM, Chan CS, Lőrincz ML, Crunelli V. Suppression of Hyperpolarization-
Activated Cyclic Nucleotide-Gated Channel Function in Thalamocortical Neurons
Prevents Genetically Determined and Pharmacologically Induced Absence Seizures.
J Neurosci. 2018 Jul 25;38(30):6615-6627. doi: 10.1523/JNEUROSCI.0896-17.2018.
Epub 2018 Jun 20. PMID: 29925625; PMCID: PMC6067077.

15: Baud MO, Perneger T, Rácz A, Pensel MC, Elger C, Rydenhag B, Malmgren K,
Cross JH, McKenna G, Tisdall M, Lamberink HJ, Rheims S, Ryvlin P, Isnard J,
Mauguière F, Arzimanoglou A, Akkol S, Deniz K, Ozkara C, Lossius M, Rektor I,
Kälviäinen R, Vanhatalo LM, Dimova P, Minkin K, Staack AM, Steinhoff BJ, Kalina
A, Krsek P, Marusic P, Jordan Z, Fabo D, Carrette E, Boon P, Rocka S,
Mameniškienė R, Vulliemoz S, Pittau F, Braun KPJ, Seeck M. European trends in
epilepsy surgery. Neurology. 2018 Jul 10;91(2):e96-e106. doi:
10.1212/WNL.0000000000005776. Epub 2018 Jun 13. PMID: 29898967.

16: Papp P, Kovács Z, Szocsics P, Juhász G, Maglóczky Z. Alterations in
hippocampal and cortical densities of functionally different interneurons in rat
models of absence epilepsy. Epilepsy Res. 2018 Sep;145:40-50. doi:
10.1016/j.eplepsyres.2018.05.013. Epub 2018 May 31. PMID: 29885592.

17: Lukacs P, Földi MC, Valánszki L, Casanova E, Biri-Kovács B, Nyitray L,
Málnási-Csizmadia A, Mike A. Non-blocking modulation contributes to sodium
channel inhibition by a covalently attached photoreactive riluzole analog. Sci
Rep. 2018 May 25;8(1):8110. doi: 10.1038/s41598-018-26444-y. PMID: 29802266;
PMCID: PMC5970139.

18: Lakatos RK, Dobolyi Á, Kovács Z. Uric acid and allopurinol aggravate absence
epileptic activity in Wistar Albino Glaxo Rijswijk rats. Brain Res. 2018 May
1;1686:1-9. doi: 10.1016/j.brainres.2018.02.012. Epub 2018 Feb 16. PMID:
29457994.

19: Hagler DJ Jr, Ulbert I, Wittner L, Erőss L, Madsen JR, Devinsky O, Doyle W,
Fabó D, Cash SS, Halgren E. Heterogeneous Origins of Human Sleep Spindles in
Different Cortical Layers. J Neurosci. 2018 Mar 21;38(12):3013-3025. doi:
10.1523/JNEUROSCI.2241-17.2018. Epub 2018 Feb 15. PMID: 29449429; PMCID:
PMC5864151.

20: Halgren M, Fabó D, Ulbert I, Madsen JR, Erőss L, Doyle WK, Devinsky O,
Schomer D, Cash SS, Halgren E. Superficial Slow Rhythms Integrate Cortical
Processing in Humans. Sci Rep. 2018 Feb 1;8(1):2055. doi:
10.1038/s41598-018-20662-0. PMID: 29391596; PMCID: PMC5794750.

21: Nair J, Klaassen AL, Arato J, Vyssotski AL, Harvey M, Rainer G. Basal
forebrain contributes to default mode network regulation. Proc Natl Acad Sci U S
A. 2018 Feb 6;115(6):1352-1357. doi: 10.1073/pnas.1712431115. Epub 2018 Jan 23.
PMID: 29363595; PMCID: PMC5819396.

22: Merikanto I, Kuula L, Makkonen T, Bódizs R, Halonen R, Heinonen K, Lahti J,
Räikkönen K, Pesonen AK. Publisher Correction: Circadian preference towards
morningness is associated with lower slow sleep spindle amplitude and intensity
in adolescents. Sci Rep. 2018 Jan 23;8(1):1662. doi: 10.1038/s41598-018-20335-y.
Erratum for: Sci Rep. 2017 Nov 6;7(1):14619. PMID: 29362407; PMCID: PMC5780520.

23: Horváth A, Szűcs A, Hidasi Z, Csukly G, Barcs G, Kamondi A. Prevalence,
Semiology, and Risk Factors of Epilepsy in Alzheimer's Disease: An Ambulatory
EEG Study. J Alzheimers Dis. 2018;63(3):1045-1054. doi: 10.3233/JAD-170925.
PMID: 29710705.

24: Tóth K, Hofer KT, Kandrács Á, Entz L, Bagó A, Erőss L, Jordán Z, Nagy G,
Sólyom A, Fabó D, Ulbert I, Wittner L. Hyperexcitability of the network
contributes to synchronization processes in the human epileptic neocortex. J
Physiol. 2018 Jan 15;596(2):317-342. doi: 10.1113/JP275413. Epub 2017 Dec 28.
PMID: 29178354; PMCID: PMC5767700.

25: Szabó A, Czakó M, Hadzsiev K, Duga B, Bánfai Z, Komlósi K, Melegh B. Small
supernumerary marker chromosome 15 and a ring chromosome 15 associated with a
15q26.3 deletion excluding the IGF1R gene. Am J Med Genet A. 2018
Feb;176(2):443-449. doi: 10.1002/ajmg.a.38566. Epub 2017 Dec 11. PMID: 29226546.

26: Mégevand P, Groppe DM, Bickel S, Mercier MR, Goldfinger MS, Keller CJ, Entz
L, Mehta AD. The Hippocampus and Amygdala Are Integrators of Neocortical
Influence: A CorticoCortical Evoked Potential Study. Brain Connect. 2017
Dec;7(10):648-660. doi: 10.1089/brain.2017.0527. PMID: 28978234; PMCID:
PMC5915225.

27: Milenkovic I, Stojanovic T, Aronica E, Fülöp L, Bozsó Z, Máté Z, Yanagawa Y,
Adle-Biassette H, Lubec G, Szabó G, Harkany T, Kovács GG, Keimpema E.
GABA<sub>A</sub> receptor subunit deregulation in the hippocampus of human
foetuses with Down syndrome. Brain Struct Funct. 2018 Apr;223(3):1501-1518. doi:
10.1007/s00429-017-1563-3. Epub 2017 Nov 22. PMID: 29168008; PMCID: PMC5869939.

28: Merikanto I, Kuula L, Makkonen T, Bódizs R, Halonen R, Heinonen K, Lahti J,
Räikkönen K, Pesonen AK. Circadian preference towards morningness is associated
with lower slow sleep spindle amplitude and intensity in adolescents. Sci Rep.
2017 Nov 6;7(1):14619. doi: 10.1038/s41598-017-13846-7. Erratum in: Sci Rep.
2018 Jan 23;8(1):1662. PMID: 29097698; PMCID: PMC5668430.

29: Li S, Kumar T P, Joshee S, Kirschstein T, Subburaju S, Khalili JS, Kloepper
J, Du C, Elkhal A, Szabó G, Jain RK, Köhling R, Vasudevan A. Endothelial cell-
derived GABA signaling modulates neuronal migration and postnatal behavior. Cell
Res. 2018 Feb;28(2):221-248. doi: 10.1038/cr.2017.135. Epub 2017 Oct 31. PMID:
29086765; PMCID: PMC5799810.

30. Fogarasi A, Erdélyi F, Siegler Zs, Hegyi M, Jakus R, Gyorsok Zs, Bodó T, Ambrus B.: Challenges in the treatment of West syndrome. Biomed J Sci & Tech Res, 2018;6,5186-9.

31: Horváth A, Szűcs A, Barcs G, Fabó D, Kelemen A, Halász P, Erőss L, Kamondi
A. Interictal Epileptiform Activity in the Foramen Ovale Electrodes of a
Frontotemporal Dementia Patient. J Alzheimers Dis Rep. 2017 Sep 13;1(1):89-96.
doi: 10.3233/ADR-170020. PMID: 30480231; PMCID: PMC6159658.

32: Kozák LR, van Graan LA, Chaudhary UJ, Szabó ÁG, Lemieux L. ICN_Atlas:
Automated description and quantification of functional MRI activation patterns
in the framework of intrinsic connectivity networks. Neuroimage. 2017
Dec;163:319-341. doi: 10.1016/j.neuroimage.2017.09.014. Epub 2017 Sep 9. PMID:
28899742; PMCID: PMC5725313.

33: Nagy E, Major A, Farkas N, Hollódy K. Epileptic seizure or not? Proportion
of correct judgement based only on a video recording of a paroxysmal event.
Seizure. 2017 Dec;53:26-30. doi: 10.1016/j.seizure.2017.08.017. Epub 2017 Sep 6.
PMID: 29101825.

34. Fogarasi A, Gyorsok Z, Bodó T. Surveillance and management of patients with tuberous sclerosis complex. Ideggyogy Sz. 2017;70(3-4):97-103. IF: 0,49

35: Szucs A, Horvath A, Fabo D, Szabo G, Kovacs A, Halasz P. Psychiatric disorders in epilepsy:
clinical phenomena. Neuropsychopharmacol Hung. 2017 Sep;19(3):147-158.
Hungarian. PMID: 29306906.

36: Ujma PP, Halász P, Kelemen A, Fabó D, Erőss L. Epileptic interictal
discharges are more frequent during NREM slow wave downstates. Neurosci Lett.
2017 Sep 29;658:37-42. doi: 10.1016/j.neulet.2017.08.020. Epub 2017 Aug 12.
PMID: 28811195.

37: Kovács Z, D'Agostino DP, Dobolyi A, Ari C. Adenosine A1 Receptor Antagonism
Abolished the Anti-seizure Effects of Exogenous Ketone Supplementation in Wistar
Albino Glaxo Rijswijk Rats. Front Mol Neurosci. 2017 Jul 25;10:235. doi:
10.3389/fnmol.2017.00235. PMID: 28790891; PMCID: PMC5524776.

38: Kozák G, Berényi A. Sustained efficacy of closed loop electrical stimulation
for long-term treatment of absence epilepsy in rats. Sci Rep. 2017 Jul
24;7(1):6300. doi: 10.1038/s41598-017-06684-0. PMID: 28740261; PMCID:
PMC5524708.

37: Kováts D, Császár N, Haller J, Juhos V, Sallay V, Békés J, Kelemen A, Fabó
D, Rásonyi G, Folyovich A, Kurimay T. Factors affecting quality of life in
Hungarian adults with epilepsy: A comparison of four psychiatric instruments.
Epilepsy Behav. 2017 Sep;74:45-58. doi: 10.1016/j.yebeh.2017.04.035. Epub 2017
Jul 5. PMID: 28686907.

39: Halász P. Comment on Neuronal networks in epileptic encephalopathies with
CSWS. Epilepsia. 2017 Jul;58(7):1296-1297. doi: 10.1111/epi.13674. PMID:
28677855.

40: Lorincz BA, Anson A, Csébi P, Bajzik G, Biró G, Tichy A, Lorincz BB,
Garamvölgyi R. Novel approach to magnetic resonance imaging of epileptic dogs -
T2 relaxometry of the brain with emphasised hippocampus. Acta Vet Hung. 2017
Jun;65(2):185-197. doi: 10.1556/004.2017.019. PMID: 28605962.

41: Nadasdy Z, Nguyen TP, Török Á, Shen JY, Briggs DE, Modur PN, Buchanan RJ.
Context-dependent spatially periodic activity in the human entorhinal cortex.
Proc Natl Acad Sci U S A. 2017 Apr 25;114(17):E3516-E3525. doi:
10.1073/pnas.1701352114. Epub 2017 Apr 10. PMID: 28396399; PMCID: PMC5410836.

42: Kitz S, Thalhammer JG, Glantschnigg U, Wrzosek M, Klang A, Halasz P, Shouse
MN, Pakozdy A. Feline Temporal Lobe Epilepsy: Review of the Experimental
Literature. J Vet Intern Med. 2017 May;31(3):633-640. doi: 10.1111/jvim.14699.
Epub 2017 Apr 6. PMID: 28382749; PMCID: PMC5435036.

43: Dömötör J, Clemens B, Puskás S, Fekete I. Decrease of global current source
density predicts successful treatment in absence and juvenile myoclonic
epilepsies. Epilepsy Res. 2017 Jul;133:1-5. doi:
10.1016/j.eplepsyres.2017.03.006. Epub 2017 Apr 2. PMID: 28391029.

44: Kardos J, Héja L, Jemnitz K, Kovács R, Palkovits M. The nature of early
astroglial protection-Fast activation and signaling. Prog Neurobiol. 2017
Jun;153:86-99. doi: 10.1016/j.pneurobio.2017.03.005. Epub 2017 Mar 22. PMID:
28342942.

45: Horváth L, Fekete K, Márton S, Fekete I. Correlation between prescribed
daily dose, seizure freedom and defined daily dose in antiepileptic drug
treatment. Int J Clin Pharm. 2017 Apr;39(2):459-467. doi:
10.1007/s11096-017-0447-1. Epub 2017 Mar 2. PMID: 28255953.

46: Vogt VL, Äikiä M, Del Barrio A, Boon P, Borbély C, Bran E, Braun K, Carette
E, Clark M, Cross JH, Dimova P, Fabo D, Foroglou N, Francione S, Gersamia A,
Gil-Nagel A, Guekht A, Harrison S, Hecimovic H, Heminghyt E, Hirsch E, Javurkova
A, Kälviäinen R, Kavan N, Kelemen A, Kimiskidis VK, Kirschner M, Kleitz C,
Kobulashvili T, Kosmidis MH, Kurtish SY, Lesourd M, Ljunggren S, Lossius MI,
Malmgren K, Mameniskiené R, Martin-Sanfilippo P, Marusic P, Miatton M, Özkara Ç,
Pelle F, Rubboli G, Rudebeck S, Ryvlin P, van Schooneveld M, Schmid E, Schmidt
PM, Seeck M, Steinhoff BJ, Shavel-Jessop S, Tarta-Arsene O, Trinka E, Viggedal
G, Wendling AS, Witt JA, Helmstaedter C; E-PILEPSY consortium. Current standards
of neuropsychological assessment in epilepsy surgery centers across Europe.
Epilepsia. 2017 Mar;58(3):343-355. doi: 10.1111/epi.13646. Epub 2017 Jan 9.
PMID: 28067423.

47: Kovács Z, Lakatos RK, Barna J, Dobolyi Á. Absence epileptic activity in
Wistar Albino Glaxo Rijswijk rat mothers. Brain Res. 2017 Feb 15;1657:368-376.
doi: 10.1016/j.brainres.2017.01.005. Epub 2017 Jan 5. PMID: 28065565.

48: Wittner L, Maglóczky Z. Synaptic Reorganization of the Perisomatic
Inhibitory Network in Hippocampi of Temporal Lobe Epileptic Patients. Biomed Res
Int. 2017;2017:7154295. doi: 10.1155/2017/7154295. Epub 2017 Jan 2. PMID:
28116310; PMCID: PMC5237728.

49: Tényi D, Gyimesi C, Kupó P, Horváth R, Bóné B, Barsi P, Kovács N, Simor T,
Siegler Z, Környei L, Fogarasi A, Janszky J. Ictal asystole: A systematic
review. Epilepsia. 2017 Mar;58(3):356-362. doi: 10.1111/epi.13644. Epub 2016 Dec
18. PMID: 27988965.

50: Erdő F, Denes L, de Lange E. Age-associated physiological and pathological
changes at the blood-brain barrier: A review. J Cereb Blood Flow Metab. 2017
Jan;37(1):4-24. doi: 10.1177/0271678X16679420. Epub 2016 Nov 11. PMID: 27837191;
PMCID: PMC5363756.

 

Summary of Activities:

One national congress (April, 2018) and one epilepsy educational program (October, 2018).

Educational scholarship for two young clinical epileptologists (2017-2020).

Challenges:

Availability and support of some AEDs.

Future Plans:

Further educational scholarships announced.

Officer Election Date: October, 2019