ILAE-North America

News

Nature Reviews Neurology
Clinical Research

Neuroinflammatory pathways as treatment targets and biomarkers in epilepsy

In this Review, we focus on our understanding of the IL-1 receptor–Toll-like receptor 4 axis, the arachidonic acid–prostaglandin cascade, oxidative stress and transforming growth factor-β signalling associated with blood–brain barrier dysfunction, all of which are pathways that are activated in pharmacoresistant epilepsy in humans and that can be modulated in animal models to produce therapeutic effects on seizures, neuronal cell loss and neurological comorbidities.

30 July, 2019
Epilepsy Specialist Nurses The Evidence (ESPENTE): a Systematic Mapping Review
World News

Epilepsy Specialist Nurses The Evidence (ESPENTE): A systematic mapping review

Epilepsy Specialist Nurses (ESNs) have been called ‘the glue that connects services to people with epilepsy’. They are in an ideal position to act as an expert resource and point of first contact for patients, carers and professionals alike. The ESPENTE study creates much needed context to the argument for the development of the ESN as an integral part of the care provided to people with epilepsy, their family and carers.

17 July, 2019